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Gene Information

Gene symbol: CCL7

Gene name: chemokine (C-C motif) ligand 7

HGNC ID: 10634

Synonyms: MCP-3, NC28, FIC, MARC, MCP3

Related Genes

#	Gene Symbol	Number of hits
1	CCL2	1 hits
2	CLEC11A	1 hits
3	CXCL10	1 hits
4	CXCL11	1 hits
5	GADD45G	1 hits
6	GORASP1	1 hits
7	IL10	1 hits
8	IL12A	1 hits
9	IL4	1 hits
10	IL5	1 hits
11	SOCS1	1 hits
12	STAT4	1 hits

Related Sentences

#	PMID	Sentence
1	20027288	Allergen challenge induces Ifng dependent GTPases in the lungs as part of a Th1 transcriptome response in a murine model of allergic asthma.
2	20027288	Consistent with our hypothesis, RWE challenge concurrently upregulated Th1-associated early target genes of the Il12/Stat4 pathway, such as p47 and p65 GTPases (Iigp, Tgtp and Gbp1), Socs1, Cxcl9, Cxcl10 and Gadd45g with the Th2 genes Il4, Il5, Ccl2 and Ccl7.
3	20027288	Augmentation of the local Th1 milieu by administration of Il12 or CpG prior to RWE challenge further upregulated these Th1 genes.
4	20027288	Abolition of the Th1 response by disrupting the Ifng gene increased allergic airway inflammation and abrogated RWE challenge-induced upregulation of GTPases, Cxcl9, Cxcl10 and Socs1, but not Gadd45g.
5	20027288	Our data demonstrate that allergen challenge induces two sets of Th1-associated genes in the lungs: 1) Ifng-dependent genes such as p47 and p65 GTPases, Socs1, Cxcl9 and Cxcl10 and 2) Ifng-independent Th1-inducing genes like Gadd45g.
6	19800444	Using real-time PCR array analysis, we could show that a group of 13 common cytokine genes are activated in the vagina within 24h after vaginal administration of these adjuvants, including Ccl2, Ccl7, Ccl12, Ccl19, Ccl20, Ccl22, Cxcl1, Cxcl5, Il10 and the Th1-inducing molecules Ifng, Cxcl9, Cxcl10 and Cxcl11.