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Gene Information

Gene symbol: CD3E

Gene name: CD3e molecule, epsilon (CD3-TCR complex)

HGNC ID: 1674

Related Genes

# Gene Symbol Number of hits
1 CD8A 1 hits
2 EOMES 1 hits
3 IFNG 1 hits
4 IL2RB 1 hits

Related Sentences

# PMID Sentence
1 22875907 CD3E (CD3)-IL2RB (CD122)+DBA cells were identified as the dominant Ifng transcript source.
2 22875907 In contrast, CD3E-IL2RB+DBA+ uNK cells expressed genes compatible with significantly greater potential for IL22 synthesis, angiogenesis, and participation in regulation mediated by the renin-angiotensin system (RAS).
3 25387892 Combination of 4-1BB agonist and PD-1 antagonist promotes antitumor effector/memory CD8 T cells in a poorly immunogenic tumor model.
4 25387892 The activity of the anti-4-1BB/anti-PD-1 combination was dependent on IFNγ and CD8(+) T cells.
5 25387892 Both 4-1BB and PD-1 proteins were elevated on the surface of CD8(+) T cells by anti-4-1BB/anti-PD-1 cotreatment.
6 25387892 In the tumor microenvironment, an effective antitumor immune response was induced as indicated by the increased CD8(+)/Treg ratio and the enrichment of genes such as Cd3e, Cd8a, Ifng, and Eomes.