Ignet

Gene Information

Gene symbol: CXCR5

Gene name: chemokine (C-X-C motif) receptor 5

HGNC ID: 1060

Synonyms: MDR15, CD185

Related Genes

#	Gene Symbol	Number of hits
1	BCL6	1 hits
2	BTLA	1 hits
3	CD69	1 hits
4	ICOS	1 hits
5	IFNG	1 hits
6	IL10	1 hits
7	IL17C	1 hits
8	PDCD1	1 hits
9	TBX21	1 hits

Related Sentences

#	PMID	Sentence
1	27531854	These cells were the major source of IL21 in tumors and represented about 10% of the CD4⁺ T-cell population at levels comparable with the T_FH cells present in lymph nodes.
2	27531854	However, these T_FH-like cells displayed a unique CXCR5^-PD-1^lo/-BTLA^-CD69^hi tissue-resident phenotype with substantial IFNγ production, which differed from the phenotype of T_FH cells.
3	27531854	Toll-like receptor 4 (TLR4)-elicited innate monocyte inflammation was important for IL21⁺ T_FH-like cell induction in tumors, and activation of STAT1 and STAT3 was critical for T_FH-like cell polarization in this process.
4	26646149	IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.
5	26646149	IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.
6	26646149	IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.
7	26646149	In Plasmodium chabaudi infection, one specific CD4 T cell subset generates anti-parasitic IFN-γ and the antibody-promoting cytokine, IL-21.
8	26646149	In Plasmodium chabaudi infection, one specific CD4 T cell subset generates anti-parasitic IFN-γ and the antibody-promoting cytokine, IL-21.
9	26646149	In Plasmodium chabaudi infection, one specific CD4 T cell subset generates anti-parasitic IFN-γ and the antibody-promoting cytokine, IL-21.
10	26646149	While Ifng+ Teff expanded, the level of the Th1 lineage-determining transcription factor T-bet only peaked briefly.
11	26646149	While Ifng+ Teff expanded, the level of the Th1 lineage-determining transcription factor T-bet only peaked briefly.
12	26646149	While Ifng+ Teff expanded, the level of the Th1 lineage-determining transcription factor T-bet only peaked briefly.
13	26646149	Ifng+ Teff also co-express ICOS, the B cell area homing molecule CXCR5, and other Tfh lineage-associated molecules including Bcl6, the transcription factor required for germinal center (GC) T follicular helper cells (Tfh) differentiation.
14	26646149	Ifng+ Teff also co-express ICOS, the B cell area homing molecule CXCR5, and other Tfh lineage-associated molecules including Bcl6, the transcription factor required for germinal center (GC) T follicular helper cells (Tfh) differentiation.
15	26646149	Ifng+ Teff also co-express ICOS, the B cell area homing molecule CXCR5, and other Tfh lineage-associated molecules including Bcl6, the transcription factor required for germinal center (GC) T follicular helper cells (Tfh) differentiation.
16	26646149	Because Bcl6 and T-bet co-localize to the nucleus of Ifng+ Teff, we hypothesized that Bcl6 controls the Tfh-like phenotype of Ifng+ Teff cells in P. chabaudi infection.
17	26646149	Because Bcl6 and T-bet co-localize to the nucleus of Ifng+ Teff, we hypothesized that Bcl6 controls the Tfh-like phenotype of Ifng+ Teff cells in P. chabaudi infection.
18	26646149	Because Bcl6 and T-bet co-localize to the nucleus of Ifng+ Teff, we hypothesized that Bcl6 controls the Tfh-like phenotype of Ifng+ Teff cells in P. chabaudi infection.
19	26646149	Bcl6-deficient T cells did not develop into GC Tfh, but they still generated CXCR5+ IFN-γ+ IL-21+ IL-10+ Teff, suggesting that this predominant population is not of the Tfh-lineage.
20	26646149	Bcl6-deficient T cells did not develop into GC Tfh, but they still generated CXCR5+ IFN-γ+ IL-21+ IL-10+ Teff, suggesting that this predominant population is not of the Tfh-lineage.
21	26646149	Bcl6-deficient T cells did not develop into GC Tfh, but they still generated CXCR5+ IFN-γ+ IL-21+ IL-10+ Teff, suggesting that this predominant population is not of the Tfh-lineage.
22	26646149	IL-10 deficient mice, which have increased IFN-γ and T-bet expression, demonstrated expansion of both IFN-γ+ IL-21+ CXCR5+ cells and IFN-γ+ GC Tfh cells, suggesting a Th1 lineage for the former.
23	26646149	IL-10 deficient mice, which have increased IFN-γ and T-bet expression, demonstrated expansion of both IFN-γ+ IL-21+ CXCR5+ cells and IFN-γ+ GC Tfh cells, suggesting a Th1 lineage for the former.
24	26646149	IL-10 deficient mice, which have increased IFN-γ and T-bet expression, demonstrated expansion of both IFN-γ+ IL-21+ CXCR5+ cells and IFN-γ+ GC Tfh cells, suggesting a Th1 lineage for the former.
25	26646149	In the memory phase, all Ifng+ T cells produced IL-21, but only a small percentage of highly proliferative Ifng+ T cells maintained a T-bethi phenotype.
26	26646149	In the memory phase, all Ifng+ T cells produced IL-21, but only a small percentage of highly proliferative Ifng+ T cells maintained a T-bethi phenotype.
27	26646149	In the memory phase, all Ifng+ T cells produced IL-21, but only a small percentage of highly proliferative Ifng+ T cells maintained a T-bethi phenotype.