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Gene Information
Gene symbol: CYP17A1
Gene name: cytochrome P450, family 17, subfamily A, polypeptide 1
HGNC ID: 2593
Synonyms: P450C17, CPT7, S17AH
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IFNG | 1 hits |
| 2 | IL1B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 28707358 | CNS tissues from patients with MS and animals with experimental autoimmune encephalomyelitis (EAE) displayed reduced DHEA concentrations, accompanied by diminished expression of the DHEA-synthesizing enzyme CYP17A1 in oligodendrocytes (ODCs), in association with increased expression of inflammatory genes including interferon (IFN)-γ and interleukin (IL)-1β. |
| 2 | 28707358 | Animals with EAE receiving DHEA-S treatment showed reduced Il1b and Ifng transcript levels in spinal cord compared to vehicle-treated animals with EAE. |