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Gene Information
Gene symbol: CYP27B1
Gene name: cytochrome P450, family 27, subfamily B, polypeptide 1
HGNC ID: 2606
Synonyms: CYP1, P450c1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
22896638
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The Ifng gene is essential for Vdr gene expression and vitamin D₃-mediated reduction of the pathogenic T cell burden in the central nervous system in experimental autoimmune encephalomyelitis, a multiple sclerosis model.
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2 |
22896638
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The two strains did not differ in Cyp27b1 and Cyp24a1 gene expression, implying equivalent vitamin D3 metabolism in the CNS.
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3 |
22896638
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Thus, the Ifng gene was needed for CNS Vdr gene expression and vitamin D3-dependent mechanisms that inhibit EAE.
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4 |
22896638
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Individuals with inadequate Ifng expression may have increased MS risk despite high ambient UV irradiation because of low Vdr gene expression and a high encephalitogenic T cell burden in the CNS.
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