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Gene Information

Gene symbol: CYP27B1

Gene name: cytochrome P450, family 27, subfamily B, polypeptide 1

HGNC ID: 2606

Synonyms: CYP1, P450c1

Related Genes

# Gene Symbol Number of hits
1 CYP24A1 1 hits

Related Sentences

# PMID Sentence
1 22896638 The Ifng gene is essential for Vdr gene expression and vitamin D₃-mediated reduction of the pathogenic T cell burden in the central nervous system in experimental autoimmune encephalomyelitis, a multiple sclerosis model.
2 22896638 The two strains did not differ in Cyp27b1 and Cyp24a1 gene expression, implying equivalent vitamin D3 metabolism in the CNS.
3 22896638 Thus, the Ifng gene was needed for CNS Vdr gene expression and vitamin D3-dependent mechanisms that inhibit EAE.
4 22896638 Individuals with inadequate Ifng expression may have increased MS risk despite high ambient UV irradiation because of low Vdr gene expression and a high encephalitogenic T cell burden in the CNS.