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Gene Information

Gene symbol: EIF4E

Gene name: eukaryotic translation initiation factor 4E

HGNC ID: 3287

Synonyms: EIF4E1

Related Genes

# Gene Symbol Number of hits
1 MKNK1 1 hits

Related Sentences

# PMID Sentence
1 28611474 p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells.
2 28611474 p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells.
3 28611474 The p38 mitogen-activated protein kinase (MAPK) pathway is involved in the regulation of immune and inflammatory processes.
4 28611474 The p38 mitogen-activated protein kinase (MAPK) pathway is involved in the regulation of immune and inflammatory processes.
5 28611474 We used p38α-conditional, p38β-deficient and p38α/β double-null mouse models to address the role of these two p38 MAPK in CD4+ T cells, and found that p38α deficiency causes these cells to hyperproliferate.
6 28611474 We used p38α-conditional, p38β-deficient and p38α/β double-null mouse models to address the role of these two p38 MAPK in CD4+ T cells, and found that p38α deficiency causes these cells to hyperproliferate.
7 28611474 Our studies indicate that both p38α and p38β are dispensable for T helper cell type 1 (Th1) differentiation but, by controlling interferon (IFN)γ and tumor necrosis factor (TNF)α production, are critical for normal Th1 effector function.
8 28611474 Our studies indicate that both p38α and p38β are dispensable for T helper cell type 1 (Th1) differentiation but, by controlling interferon (IFN)γ and tumor necrosis factor (TNF)α production, are critical for normal Th1 effector function.
9 28611474 Our results indicate that p38α regulates IFNγ secretion through the activation of the MNK1/eIF4E pathway of translation initiation and identify specific functions for p38α and p38β in T-cell proliferation.
10 28611474 Our results indicate that p38α regulates IFNγ secretion through the activation of the MNK1/eIF4E pathway of translation initiation and identify specific functions for p38α and p38β in T-cell proliferation.