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Gene Information
Gene symbol: ESAM
Gene name: endothelial cell adhesion molecule
HGNC ID: 17474
Synonyms: W117m
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CADM1 | 1 hits |
| 2 | CDH13 | 1 hits |
| 3 | CDH17 | 1 hits |
| 4 | CSF1 | 1 hits |
| 5 | CXCL1 | 1 hits |
| 6 | DSG4 | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | PECAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 26956486 | We found that the cell surface molecule platelet endothelial cell adhesion molecule-1 (PECAM-1) facilitated noncanonical (Smad-independent) TGF-β signaling in T cells. |
| 2 | 26956486 | T cells isolated from PECAM-1(-/-) mice demonstrated relative insensitivity to the TGF-β-dependent inhibition of interferon-γ (IFN-γ) production, granzyme B synthesis, and cellular proliferation. |
| 3 | 26956486 | Co-incubation of T cells with TGF-β and a T cell-activating antibody resulted in PECAM-1 phosphorylation on an immunoreceptor tyrosine-based inhibitory motif (ITIM) and the recruitment of the inhibitory Src homology 2 (SH2) domain-containing tyrosine phosphatase-2 (SHP-2). |
| 4 | 25965835 | These included cadherin 13 (Cdh13), colony stimulating factor 1 (Csf1), chemokine C-X-C motif ligand 1 (Cxcl1), endothelial cell-selective adhesion molecule (Esam), and interferon gamma (Ifng). |