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Gene Information
Gene symbol: EZH1
Gene name: enhancer of zeste homolog 1 (Drosophila)
HGNC ID: 3526
Synonyms: KIAA0388, KMT6B
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EZH2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24951427 | The epigenetic silencing of cytokine genes is associated with the repressive H3K27 trimethylation mark, mediated by the Ezh2 or Ezh1 methyltransferase components of the polycomb repressive complex 2 (PRC2). |
| 2 | 24951427 | Here we show that silencing of the Ifng, Gata3, and Il10 loci in naïve CD4(+) T cells is dependent on Ezh2. |
| 3 | 24951427 | Naïve CD4(+) T cells lacking Ezh2 were epigenetically primed for overproduction of IFN-γ in Th2 and iTreg and IL-10 in Th2 cells. |
| 4 | 24951427 | In addition, deficiency of Ezh2 accelerated effector Th cell death via death receptor-mediated extrinsic and intrinsic apoptotic pathways, confirmed in vivo for Ezh2-null IFN-γ-producing CD4(+) and CD8(+) T cells responding to Listeria monocytogenes infection. |