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Gene Information
Gene symbol: FOSL2
Gene name: FOS-like antigen 2
HGNC ID: 3798
Synonyms: FRA2, FLJ23306
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EP300 | 1 hits |
| 2 | FOS | 1 hits |
| 3 | JUN | 1 hits |
| 4 | JUND | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 26751080 | Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex. |
| 2 | 26751080 | Our previous work demonstrated that human inducible nitric oxide synthase (hiNOS) expression can be highly induced with the cytokine mixture (CM) of TNF-α + IL-1β + IFN-γ. |
| 3 | 26751080 | Site-directed mutagenesis of the hiNOS AP-1 motifs revealed that an intact upstream (-5.3 kb) AP-1 binding site was critical for p300 mediated cytokine-induced hiNOS transcription. |
| 4 | 26751080 | Furthermore, our ChIP analysis demonstrated that p300 was binding to Jun D and Fra-2 proteins at -5.3 kb AP-1 binding site in vivo. |
| 5 | 26751080 | Lastly, our 3C assay was able to detect a long DNA loop between the hiNOS enhancer and core promoter site, and ChIP loop assay confirmed that p300 binds to AP-1 and RNA pol II proteins. |