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Gene Information
Gene symbol: HLA-C
Gene name: major histocompatibility complex, class I, C
HGNC ID: 4933
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | HLA-A | 1 hits |
| 3 | HLA-DMA | 1 hits |
| 4 | HLA-DMB | 1 hits |
| 5 | HLA-DRA | 1 hits |
| 6 | HLA-F | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | IL12A | 1 hits |
| 9 | KIR3DL1 | 1 hits |
| 10 | NFKB1 | 1 hits |
| 11 | PRKCA | 1 hits |
| 12 | PSMA5 | 1 hits |
| 13 | PSMB8 | 1 hits |
| 14 | PSMB9 | 1 hits |
| 15 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25774455 | Genes that were significantly regulated between VRs and VNRs were CREB3L4, HIST1H3A, HIST1H3H, IFNA1, IFNA4, IFNA5, IFNA6, IFNA8, IFNA14, IFNG, IFNAR1, IL6, IRF9, MAPK4, MAPK5, MAPK14, NET1, and PIK3C2A in the IFN array. |
| 2 | 25774455 | In the TLR array, only LBP and MAPK8 were found to be differentially regulated. |
| 3 | 25774455 | In the antigen processing array, HLA-A, HLA-C, HLA-DMA, HLA-DMB, HLA-F, PSMA5, PSMB8, and PSMB9 were differentially downregulated. |
| 4 | 24954223 | In humans, specific patterns of killer immunoglobulin-like receptors (KIRs) expressed by uterine natural killer (uNK) cells are linked through HLA-C with pregnancy complications (infertility, recurrent spontaneous abortion, intrauterine growth restriction and preeclampsia). |
| 5 | 24954223 | To identify mechanisms underpinning the associations between NK cell activation and pregnancy success, pregnancies were studied in mice with genetic knockdown (KD) of the MHC-activated Ly49 receptor gene family. |
| 6 | 24954223 | At mid-pregnancy (gestation day (gd9.5)), overall uNK cell (TCRβ(-)CD122(+)DBA(+)DX5(-) (DBA(+)DX5(-))) and TCRβ(-)CD122(+)DBA(-)DX5(+) (DBA(-)DX5(+))) frequencies in pregnant uterus were similar between genotypes. |
| 7 | 24954223 | Ultrastructural analyses revealed that B6.Ly49(KD) uNK cells had impaired granulogenesis, while immunocytochemistry revealed deficient vascular endothelial cell growth factor (VEGFA) production. |
| 8 | 23071669 | These included five that were common to both ages (TNF, HNF4A, IL15, Progesterone, and YWHAZ), and others that were unique to 2 weeks (e.g. |
| 9 | 23071669 | MYC/MYCN, TGFB1, and IL2) and to 4 weeks (e.g. |
| 10 | 23071669 | IFNG, beta-estradiol, p53, NFKB, AKT, PRKCA, IL12, and HLA-C). |
| 11 | 23071669 | Based on the literature, genes that may play a role in regulating metabolic pathways at 2 weeks include Myc and HNF4A, and at 4 weeks, beta-estradiol, p53, Akt, HNF4A and AR. |
| 12 | 21067287 | Multiple sclerosis risk markers in HLA-DRA, HLA-C, and IFNG genes are associated with sex-specific childhood leukemia risk. |
| 13 | 21067287 | Two other SNPs in superkiller viralicidic activity 2-like and tenascin XB that are markers for systemic lupus erythematosus susceptibility showed female-specific associations but due to linkage disequilibrium with HLA-DRB1*15. |