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Gene Information
Gene symbol: HLA-DRA
Gene name: major histocompatibility complex, class II, DR alpha
HGNC ID: 4947
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL2 | 1 hits |
| 2 | FASLG | 1 hits |
| 3 | HLA-C | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | IL10 | 1 hits |
| 6 | IL8RB | 1 hits |
| 7 | ITGB2 | 1 hits |
| 8 | MCL1 | 1 hits |
| 9 | PPARD | 1 hits |
| 10 | PPARG | 1 hits |
| 11 | RIPK1 | 1 hits |
| 12 | SELL | 1 hits |
| 13 | STAT3 | 1 hits |
| 14 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21067287 | Multiple sclerosis risk markers in HLA-DRA, HLA-C, and IFNG genes are associated with sex-specific childhood leukemia risk. |
| 2 | 21067287 | Two other SNPs in superkiller viralicidic activity 2-like and tenascin XB that are markers for systemic lupus erythematosus susceptibility showed female-specific associations but due to linkage disequilibrium with HLA-DRB1*15. |
| 3 | 23874546 | Of these transcripts, six (TNFAIP6, FCN1, CXCL10, GBP1, CXCL5 and PID1) were differentially expressed in septic patients' blood compared to healthy blood upon ex vivo LPS stimulation and were restored by IFN-γ. |
| 4 | 23874546 | Along with the previously identified markers TNFa, IL10 and HLA-DRA, the potential value of these markers should now be evaluated in a larger cohort of patients. |
| 5 | 27179873 | Genes that were differentially expressed over the transition period included those involved in neutrophil adhesion (SELL, ITGB2, and ITGBX), mediation of the immune response (TLR4, HLA-DRA, and CXCR2), maturation, cell cycle progression, apoptosis (MCL1, BCL2, FASLG, and RIPK1), and control of gene expression (PPARG, PPARD, and STAT3). |
| 6 | 27179873 | We noted reduced gene expression of proinflammatory cytokines (IFNG, TNF, IL12, and CCL2) on the day of calving, whereas anti-inflammatory cytokine gene expression (IL10) was upregulated. |
| 7 | 27179873 | Increased gene expression of antimicrobial peptides (BNBD4, DEFB10, and DEFB1) occurred on the day of calving. |