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Gene Information
Gene symbol: HMOX1
Gene name: heme oxygenase (decycling) 1
HGNC ID: 5013
Synonyms: bK286B10, HO-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL5 | 1 hits |
| 2 | CD14 | 1 hits |
| 3 | CXCL10 | 1 hits |
| 4 | CXCL9 | 1 hits |
| 5 | GADD45A | 1 hits |
| 6 | GLI2 | 1 hits |
| 7 | GPNMB | 1 hits |
| 8 | GZMB | 1 hits |
| 9 | IFNG | 1 hits |
| 10 | IGF1 | 1 hits |
| 11 | LTF | 1 hits |
| 12 | MPO | 1 hits |
| 13 | NQO1 | 1 hits |
| 14 | S100A8 | 1 hits |
| 15 | S100A9 | 1 hits |
| 16 | TCF7L2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25877879 | Of these, the potential host responses included up-regulation of genes related to immune response (CD14, S100A8, S100A9, LTF, HP and CHCIL3), up-regulation of Th1-polarizing factor (CCL4, CCL5, CXCL9 and CXCL10), down-regulation of genes related to metabolism (ELANE, IGF1, TCF7L2 and MPO) and no significant response of other genes (GADD45a, GPNMB, HMOX1, IFNG and NQO1) in THP-1 cells infected with MAP. |
| 2 | 25196646 | Inhibition of HO-1 via SnMP in cytomegalovirus (CMV)pp65-peptide-pulsed peripheral blood mononuclear cells (PBMCs) led to increased anti-viral T cell activation and the generation of a higher proportion of effector memory T cells (CD45RA(-) CD62L(-)) with increased capability to secrete interferon (IFN)-γ and granzyme B. |
| 3 | 25196646 | Compared to control, SnMP treatment resulted in higher cell counts and purity without negative impact on quality and effector function [CD107a, IFN-γ and tumour necrosis factor (TNF)-α levels were stable]. |