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Gene Information
Gene symbol: HSD17B1
Gene name: hydroxysteroid (17-beta) dehydrogenase 1
HGNC ID: 5210
Synonyms: HSD17, MGC138140, SDR28C1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21734265
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During reprogramming of porcine mesenchymal cells with a four-factor (POU5F1/SOX2/KLF4/MYC) mixture of vectors, a fraction of the colonies had an atypical phenotype and arose earlier than the recognizable porcine induced pluripotent stem (iPS) cell colonies.
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2 |
21734265
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Relative to gene expression of the iPS cells, there was up-regulation of genes for transcription factors associated with trophoblast (TR) lineage emergence, e.g., GATA2, PPARG, MSX2, DLX3, HAND1, GCM1, CDX2, ID2, ELF5, TCFAP2C, and TEAD4 and for genes required for synthesis of products more typical of differentiated TR, such as steroids (HSD17B1, CYP11A1, and STAR), pregnancy-associated glycoproteins (PAG6), and select cytokines (IFND, IFNG, and IL1B).
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