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Gene Information
Gene symbol: ID2
Gene name: inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
HGNC ID: 5361
Synonyms: GIG8, bHLHb26
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDX2 | 1 hits |
| 2 | CYP11A1 | 1 hits |
| 3 | DLX3 | 1 hits |
| 4 | GATA2 | 1 hits |
| 5 | GCM1 | 1 hits |
| 6 | HAND1 | 1 hits |
| 7 | HSD17B1 | 1 hits |
| 8 | IFNG | 1 hits |
| 9 | IL1B | 1 hits |
| 10 | MSX2 | 1 hits |
| 11 | PPARG | 1 hits |
| 12 | STAR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21734265 | During reprogramming of porcine mesenchymal cells with a four-factor (POU5F1/SOX2/KLF4/MYC) mixture of vectors, a fraction of the colonies had an atypical phenotype and arose earlier than the recognizable porcine induced pluripotent stem (iPS) cell colonies. |
| 2 | 21734265 | Relative to gene expression of the iPS cells, there was up-regulation of genes for transcription factors associated with trophoblast (TR) lineage emergence, e.g., GATA2, PPARG, MSX2, DLX3, HAND1, GCM1, CDX2, ID2, ELF5, TCFAP2C, and TEAD4 and for genes required for synthesis of products more typical of differentiated TR, such as steroids (HSD17B1, CYP11A1, and STAR), pregnancy-associated glycoproteins (PAG6), and select cytokines (IFND, IFNG, and IL1B). |