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Gene Information
Gene symbol: IL10RB
Gene name: interleukin 10 receptor, beta
HGNC ID: 5965
Synonyms: CRF2-4, CDW210B, IL-10R2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL10 | 1 hits |
| 2 | IL13RA2 | 1 hits |
| 3 | IL20RA | 1 hits |
| 4 | SUMO1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20947410 | Interleukin-26: an IL-10-related cytokine produced by Th17 cells. |
| 2 | 20947410 | IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines. |
| 3 | 20947410 | The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22). |
| 4 | 20947410 | IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells. |
| 5 | 20947410 | It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains. |
| 6 | 20947410 | Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes. |
| 7 | 28063951 | The results showed differential expression of host genes related to response to stress, immune response and protein folding (genes such as; atf3, mhc, mx1-3, cd276, cd2, cocs1, c7, il10, il10rb, il13ra2, ubl-1, ifng, ifngr1, hivep2, sigle14 and sigle5). |