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Gene Information
Gene symbol: IL20RA
Gene name: interleukin 20 receptor, alpha
HGNC ID: 6003
Synonyms: ZCYTOR7, IL-20R1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
20947410
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Interleukin-26: an IL-10-related cytokine produced by Th17 cells.
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2 |
20947410
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IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines.
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3 |
20947410
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The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22).
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4 |
20947410
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IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells.
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5 |
20947410
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It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains.
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6 |
20947410
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Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes.
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