Ignet

Gene Information

Gene symbol: IL26

Gene name: interleukin 26

HGNC ID: 17119

Synonyms: AK155, IL-26

Related Genes

#	Gene Symbol	Number of hits
1	DYRK2	1 hits
2	IFNG	1 hits
3	IL10	1 hits
4	IL17A	1 hits
5	IL17D	1 hits
6	IL22	1 hits
7	MDM1	1 hits
8	STAT1	1 hits
9	STAT3	1 hits
10	TJP1	1 hits

Related Sentences

#	PMID	Sentence
1	12486605	Among these the most striking ones are the genes coding for the cytokines interleukin-22 (IL-22) and interleukin-26 (IL-26) that constitute together with IFNG a cytokine cluster on chromosome 12q14.
2	15858598	Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region.
3	15858598	We began by analysing West African and European haplotype structure and patterns of linkage disequilibrium across a 100 kb genomic region encompassing IFNG and its immediate neighbours IL22 and IL26.
4	15858598	A large case-control study of severe malaria in a West Africa population identified several weak associations with individual single-nucleotide polymorphisms in the IFNG and IL22 genes, and defined two IL22 haplotypes that are, respectively, associated with resistance and susceptibility.
5	15858598	Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region.
6	15858598	We began by analysing West African and European haplotype structure and patterns of linkage disequilibrium across a 100 kb genomic region encompassing IFNG and its immediate neighbours IL22 and IL26.
7	15858598	A large case-control study of severe malaria in a West Africa population identified several weak associations with individual single-nucleotide polymorphisms in the IFNG and IL22 genes, and defined two IL22 haplotypes that are, respectively, associated with resistance and susceptibility.
8	17546033	Here our evolutionary analysis showed that the mouse Ifng locus diverged from the ancestral locus as a result of structural rearrangements producing deletion of the neighboring gene encoding interleukin 26 and disrupting synteny 57 kilobases upstream of Ifng.
9	20947410	Interleukin-26: an IL-10-related cytokine produced by Th17 cells.
10	20947410	IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines.
11	20947410	The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22).
12	20947410	IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells.
13	20947410	It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains.
14	20947410	Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes.
15	20947410	Interleukin-26: an IL-10-related cytokine produced by Th17 cells.
16	20947410	IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines.
17	20947410	The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22).
18	20947410	IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells.
19	20947410	It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains.
20	20947410	Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes.
21	20947410	Interleukin-26: an IL-10-related cytokine produced by Th17 cells.
22	20947410	IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines.
23	20947410	The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22).
24	20947410	IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells.
25	20947410	It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains.
26	20947410	Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes.
27	20947410	Interleukin-26: an IL-10-related cytokine produced by Th17 cells.
28	20947410	IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines.
29	20947410	The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22).
30	20947410	IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells.
31	20947410	It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains.
32	20947410	Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes.
33	20947410	Interleukin-26: an IL-10-related cytokine produced by Th17 cells.
34	20947410	IL-26 is classified as a member of the IL-10 cytokine family because it has limited sequence homology to IL-10 and the IL-10-related cytokines.
35	20947410	The human IL-26 gene, IL26, is located on chromosome 12q15 between the genes for two other important class-2 cytokines, IFNG (IFN-γ) and IL22 (IL-22).
36	20947410	IL-26 is often co-expressed with IL-22 by activated T cells, especially Th17 cells.
37	20947410	It signals through a heterodimeric receptor complex composed of the IL-20R1 and IL-10R2 chains.
38	20947410	Signaling through IL-26 receptor complexes results in the activation of STAT1 and STAT3 with subsequent induction of IL-26-responsive genes.
39	23808390	Interleukin-26 (IL26) is a member of the IL10 cytokine family.
40	23808390	The IL26 gene is located between two other well-known cytokines genes of this family encoding interferon-gamma (IFNG) and IL22 in an evolutionary conserved gene cluster.
41	23808390	Interleukin-26 (IL26) is a member of the IL10 cytokine family.
42	23808390	The IL26 gene is located between two other well-known cytokines genes of this family encoding interferon-gamma (IFNG) and IL22 in an evolutionary conserved gene cluster.
43	23850722	In the gene loci of IFN-γ, DYRK2, IL22, IL26 and MDM1 are found with conserved synteny in vertebrates, and similar genes adjacent to IFN-γR1 and IFN-γR2 were also found.
44	26903715	In contrast, the Th17 cytokines IL-17, IL-22, and IL-26 showed a significant disruption of the epithelial barrier, evidenced by a loss of TEER, increased paracellular permeability of FITC-dextrans, and discontinuous ZO-1 immunolocalisation.