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Gene Information
Gene symbol: IL2RB
Gene name: interleukin 2 receptor, beta
HGNC ID: 6009
Synonyms: CD122
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD3E | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | LOH19CR1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24954223 | In humans, specific patterns of killer immunoglobulin-like receptors (KIRs) expressed by uterine natural killer (uNK) cells are linked through HLA-C with pregnancy complications (infertility, recurrent spontaneous abortion, intrauterine growth restriction and preeclampsia). |
| 2 | 24954223 | To identify mechanisms underpinning the associations between NK cell activation and pregnancy success, pregnancies were studied in mice with genetic knockdown (KD) of the MHC-activated Ly49 receptor gene family. |
| 3 | 24954223 | At mid-pregnancy (gestation day (gd9.5)), overall uNK cell (TCRβ(-)CD122(+)DBA(+)DX5(-) (DBA(+)DX5(-))) and TCRβ(-)CD122(+)DBA(-)DX5(+) (DBA(-)DX5(+))) frequencies in pregnant uterus were similar between genotypes. |
| 4 | 24954223 | Ultrastructural analyses revealed that B6.Ly49(KD) uNK cells had impaired granulogenesis, while immunocytochemistry revealed deficient vascular endothelial cell growth factor (VEGFA) production. |
| 5 | 22875907 | CD3E (CD3)-IL2RB (CD122)+DBA cells were identified as the dominant Ifng transcript source. |
| 6 | 22875907 | In contrast, CD3E-IL2RB+DBA+ uNK cells expressed genes compatible with significantly greater potential for IL22 synthesis, angiogenesis, and participation in regulation mediated by the renin-angiotensin system (RAS). |