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Gene Information
Gene symbol: IL3
Gene name: interleukin 3 (colony-stimulating factor, multiple)
HGNC ID: 6011
Synonyms: IL-3, MULTI-CSF, MCGF, MGC79398, MGC79399
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CSF2 | 1 hits |
| 2 | CSF3 | 1 hits |
| 3 | IFNG | 1 hits |
| 4 | IL15 | 1 hits |
| 5 | IL1B | 1 hits |
| 6 | IL3RA | 1 hits |
| 7 | IL4 | 1 hits |
| 8 | IL6 | 1 hits |
| 9 | IL6R | 1 hits |
| 10 | IL8 | 1 hits |
| 11 | IL8RA | 1 hits |
| 12 | IL8RB | 1 hits |
| 13 | LIF | 1 hits |
| 14 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25029985 | These cells released 1,186.7 ± 149.6 pg IL3PE38KDEL/10(4) cells over 48 h into the medium and the culture supernatant selectively killed IL3 receptor(IL3R)-positive HL60 cells, but not IL3R-negative K562 cells. |
| 2 | 22674296 | After controlling for multiple comparisons, single nucleotide polymorphisms (SNPs) from four genes, IL3, IL6R, IL8, IL15, were associated with increased colon cancer risk, and CXCR1 and CXCR2 were significantly associated with increased rectal cancer risk. |
| 3 | 22674296 | Only SNPs from genes within the IL-8 pathway (IL8, CXCR1 and CXCR2) showed a significant association with both colon and rectal cancer risk. |
| 4 | 22674296 | Several SNPs interacted significantly with IL8 and IFNG SNPs and with aspirin/non-steroidal anti-inflammatory drug (NSAID), cigarette smoking, estrogen use and BMI. |
| 5 | 20427761 | The cytokines interferon tau (IFNT), interferon gamma (IFNG), and interleukin 4 (IL4) significantly increased luciferase expression in NC1 promoter reporter constructs and endogenous NC1 mRNA levels in a bovine endometrial cell line. |
| 6 | 20427761 | In addition, IFNG, IL3, IL4, and progesterone significantly increased Day 7 bovine blastocyst NC1 mRNA expression when supplemented during in vitro embryo culture. |
| 7 | 20427761 | The promoter is responsive to IFNT, IFNG, and IL4, suggesting possible roles for these cytokines in bovine preimplantation embryo survival and/or maternal-fetal tolerance. |
| 8 | 7683736 | The differentiation inducing effects of interleukins (IL-1 beta, IL-3 and IL-6), colony stimulating factors (GCSF and GMCSF), TNF, LIF and IFNg, were studied either individually or in combination. |
| 9 | 7683736 | The differentiation inducing effects of interleukins (IL-1 beta, IL-3 and IL-6), colony stimulating factors (GCSF and GMCSF), TNF, LIF and IFNg, were studied either individually or in combination. |
| 10 | 7683736 | IL-3, IL-6, interferon gamma, GCSF and to a smaller extent IL-1 beta and GMCSF synergized the differentiation inducing activity of TNF. |
| 11 | 7683736 | IL-3, IL-6, interferon gamma, GCSF and to a smaller extent IL-1 beta and GMCSF synergized the differentiation inducing activity of TNF. |