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Gene Information
Gene symbol: IL6R
Gene name: interleukin 6 receptor
HGNC ID: 6019
Synonyms: CD126
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AFP | 1 hits |
| 2 | CSF1 | 1 hits |
| 3 | CTNNB1 | 1 hits |
| 4 | IGFBP6 | 1 hits |
| 5 | IL15 | 1 hits |
| 6 | IL3 | 1 hits |
| 7 | IL8 | 1 hits |
| 8 | IL8RA | 1 hits |
| 9 | IL8RB | 1 hits |
| 10 | VCAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22674296 | After controlling for multiple comparisons, single nucleotide polymorphisms (SNPs) from four genes, IL3, IL6R, IL8, IL15, were associated with increased colon cancer risk, and CXCR1 and CXCR2 were significantly associated with increased rectal cancer risk. |
| 2 | 22674296 | Only SNPs from genes within the IL-8 pathway (IL8, CXCR1 and CXCR2) showed a significant association with both colon and rectal cancer risk. |
| 3 | 22674296 | Several SNPs interacted significantly with IL8 and IFNG SNPs and with aspirin/non-steroidal anti-inflammatory drug (NSAID), cigarette smoking, estrogen use and BMI. |
| 4 | 19578489 | We identified 7 proteins that significantly differentiate HCC patients from hepatitis patients (p < 0.05) (AFP, CTNNB, CSF1, SELL, IGFBP6, IL6R, and VCAM1). |
| 5 | 19578489 | Importantly, we also identified 8 proteins that significantly differentiate HCC patients with 'normal' levels of AFP (< 20 ng/ml) from hepatitis patients (p < 0.05) (IL1RN, IFNG, CDKN1A, RETN, CXCL14, CTNNB, FGF2, and SELL). |