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Gene Information
Gene symbol: IRF8
Gene name: interferon regulatory factor 8
HGNC ID: 5358
Synonyms: IRF-8, ICSBP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD28 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | CD8B | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | IFNGR1 | 1 hits |
| 6 | IFNGR2 | 1 hits |
| 7 | IRF2 | 1 hits |
| 8 | IRF3 | 1 hits |
| 9 | IRF4 | 1 hits |
| 10 | IRF6 | 1 hits |
| 11 | MYD88 | 1 hits |
| 12 | TBX21 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21859832 | In this study we examine genetic variation in IFNG, IFNGR1, IFNGR2 and interferon regulatory factors (IRFs) to determine associations with colon and rectal cancer and survival after diagnosis. |
| 2 | 21859832 | Five tagSNPs in IFNG, IRF2 and IRF3 were associated with colon cancer and eight tagSNPs in IFNGR1, IFNGR2, IRF2, IRF4, IRF6 and IRF8 were associated with rectal cancer. |
| 3 | 21859832 | IRF3 rs2304204 was associated with the strongest direct association and IRF2 3775554 with the strongest inverse association for colon cancer [odds ratios (ORs) 1.43, 95% confidence interval (CI) 1.12-1.82 for recessive model and 0.52, 95% CI 0.28-0.97 for unrestricted model]. |
| 4 | 21859832 | For rectal cancer, IFNGR1 rs3799488 was directly associated with risk (OR 2.30, 95% CI 1.04-5.09 for recessive model), whereas IRF6 rs861020 was inversely associated with risk (OR 0.57, 95% CI 0.34-0.95). |
| 5 | 15183000 | This publication describes the cloning of full or partial length sequences for pig TBX21 (T-bet), MYD88, ICSBP1, CD8A (CD8alpha), CD8B (CD8beta), and CD28 cDNAs. |
| 6 | 15183000 | Real-time PCR assays have been developed for the relative quantitation of these products as well as previously characterized transcripts that encode exon A-containing CD45, HLX1, IRF1, STAT1 and RPL32. |
| 7 | 15183000 | When used for examining temporal immune gene expression in the liver of Toxoplasma gondii infected pigs, the positive regulators of Th1 responses, IRF1, MYD88, and STAT1, were found to be expressed prior to the simultaneous upregulation of interferon gamma (IFNG), HLX1 and TBX21 gene expression. |
| 8 | 15183000 | In contrast, in the mesenteric lymph node (MLN), only expression of IRF1 and IFNG was significantly upregulated. |