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Gene Information
Gene symbol: ITGB2
Gene name: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
HGNC ID: 6155
Synonyms: LFA-1, MAC-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL2 | 1 hits |
| 2 | CCR5 | 1 hits |
| 3 | CCR7 | 1 hits |
| 4 | CXCR6 | 1 hits |
| 5 | FASLG | 1 hits |
| 6 | FOS | 1 hits |
| 7 | HLA-DRA | 1 hits |
| 8 | IFNG | 1 hits |
| 9 | IL8RB | 1 hits |
| 10 | MCL1 | 1 hits |
| 11 | NFKBIA | 1 hits |
| 12 | PPARD | 1 hits |
| 13 | PPARG | 1 hits |
| 14 | RIPK1 | 1 hits |
| 15 | SELL | 1 hits |
| 16 | STAT3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 27580107 | The DNA microarray data were validated by use of a real-time reverse-transcription PCR assay, and expression of the genes FOS, NFKBI, IFNG, CXCR6, CCR5, ITGB2, CCR7, and SELL was assessed. |
| 2 | 27580107 | Profile analysis also revealed that FOS and NFKBI (genes of transcription factors) were involved in most cell-signaling pathways and that expression of these genes was significantly higher in colostral T cells than in peripheral blood T cells. |
| 3 | 27580107 | Furthermore, CCR7 and SELL (genes of T-cell differentiation markers) in colostral T cells had expression patterns extremely similar to those found in effector or effector memory T cells. |
| 4 | 27179873 | Genes that were differentially expressed over the transition period included those involved in neutrophil adhesion (SELL, ITGB2, and ITGBX), mediation of the immune response (TLR4, HLA-DRA, and CXCR2), maturation, cell cycle progression, apoptosis (MCL1, BCL2, FASLG, and RIPK1), and control of gene expression (PPARG, PPARD, and STAT3). |
| 5 | 27179873 | We noted reduced gene expression of proinflammatory cytokines (IFNG, TNF, IL12, and CCL2) on the day of calving, whereas anti-inflammatory cytokine gene expression (IL10) was upregulated. |
| 6 | 27179873 | Increased gene expression of antimicrobial peptides (BNBD4, DEFB10, and DEFB1) occurred on the day of calving. |