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Gene Information
Gene symbol: KIR2DL4
Gene name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
HGNC ID: 6332
Synonyms: 103AS, 15.212, CD158D
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IFNG | 1 hits |
| 2 | IL12A | 1 hits |
| 3 | ITGAE | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 29070650 | The increased metastasis was independent of CD4+ and CD8+ T lymphocytes, but required NK cells and IFNγ. |
| 2 | 29070650 | We found that IL12-YFP reporter mice, whose lungs were injected with B16F10 melanoma, had increased numbers of IL12-expressing CD103+ DCs with enhanced CD86 expression. |
| 3 | 29070650 | Analysis of TCGA datasets revealed an association between high expression of BATF3 and IRF8 and improved survival of breast cancer patients; BATF3 expression also significantly correlated with NK-cell receptor genes, IL12, and IFNG Collectively, our findings show that IL12 from CD103+ DCs is critical for NK cell-mediated control of tumor metastasis. |