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Gene Information

Gene symbol: LBP

Gene name: lipopolysaccharide binding protein

HGNC ID: 6517

Synonyms: BPIFD2

Related Genes

#	Gene Symbol	Number of hits
1	CD14	1 hits
2	MAPK8	1 hits
3	TNF	1 hits

Related Sentences

#	PMID	Sentence
1	25774455	Genes that were significantly regulated between VRs and VNRs were CREB3L4, HIST1H3A, HIST1H3H, IFNA1, IFNA4, IFNA5, IFNA6, IFNA8, IFNA14, IFNG, IFNAR1, IL6, IRF9, MAPK4, MAPK5, MAPK14, NET1, and PIK3C2A in the IFN array.
2	25774455	In the TLR array, only LBP and MAPK8 were found to be differentially regulated.
3	25774455	In the antigen processing array, HLA-A, HLA-C, HLA-DMA, HLA-DMB, HLA-F, PSMA5, PSMB8, and PSMB9 were differentially downregulated.
4	1724447	The 52 kD myeloid membrane glycoprotein CD14 represents the receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein (LBP); it is involved in LPS induced tumor necrosis factor-alpha production.
5	1724447	The effect of rIFNg on CD14 in PBL cultures was dose-dependently inhibited by rIL-4 and this inhibition is probably due to an IL-4 mediated blockade of IFNg secretion.
6	1724447	The results, showing that CD14 antigen expression is upregulated by LPS and downregulated by rIFNg and rIL-4, suggest that the LPS-LBP receptor is involved in the feedback response of IFNg and IL-4 to LPS stimulation.