Ignet

Gene Information

Gene symbol: LYG1

Gene name:

HGNC ID:

Related Genes

#	Gene Symbol	Number of hits
1	CD4	1 hits
2	CD8A	1 hits
3	IFNG	1 hits

Related Sentences

#	PMID	Sentence
1	28507796	LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4⁺ T cells.
2	28507796	LYG1 recombinant protein (rhLYG1) could significantly suppress the growth of B16 tumors in WT B6 mice, but not in SCID-beige mice, Rag1^-/- mice, CD4⁺- or CD8⁺ T cell-deleted mice.
3	28507796	It could increase the number of CD4⁺ and CD8⁺ T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes, and spleens, and promote IFNγ production by T cells in tumor-bearing mice.
4	28507796	In vitro experiments demonstrated that rhLYG1 could directly enhance IFNγ secretion by CD4⁺ T cells, but not CD8⁺ T cells.
5	28507796	The tumor-inhibiting effect of LYG1 was eliminated in Ifng^-/- mice.
6	28507796	In summary, our findings reveal a tumor-inhibiting role for LYG1 through promoting the activation, proliferation, and function of CD4⁺ T cells in antitumor immune responses, offering implications for novel tumor immunotherapy.
7	28507796	LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4⁺ T cells.
8	28507796	LYG1 recombinant protein (rhLYG1) could significantly suppress the growth of B16 tumors in WT B6 mice, but not in SCID-beige mice, Rag1^-/- mice, CD4⁺- or CD8⁺ T cell-deleted mice.
9	28507796	It could increase the number of CD4⁺ and CD8⁺ T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes, and spleens, and promote IFNγ production by T cells in tumor-bearing mice.
10	28507796	In vitro experiments demonstrated that rhLYG1 could directly enhance IFNγ secretion by CD4⁺ T cells, but not CD8⁺ T cells.
11	28507796	The tumor-inhibiting effect of LYG1 was eliminated in Ifng^-/- mice.
12	28507796	In summary, our findings reveal a tumor-inhibiting role for LYG1 through promoting the activation, proliferation, and function of CD4⁺ T cells in antitumor immune responses, offering implications for novel tumor immunotherapy.
13	28507796	LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4⁺ T cells.
14	28507796	LYG1 recombinant protein (rhLYG1) could significantly suppress the growth of B16 tumors in WT B6 mice, but not in SCID-beige mice, Rag1^-/- mice, CD4⁺- or CD8⁺ T cell-deleted mice.
15	28507796	It could increase the number of CD4⁺ and CD8⁺ T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes, and spleens, and promote IFNγ production by T cells in tumor-bearing mice.
16	28507796	In vitro experiments demonstrated that rhLYG1 could directly enhance IFNγ secretion by CD4⁺ T cells, but not CD8⁺ T cells.
17	28507796	The tumor-inhibiting effect of LYG1 was eliminated in Ifng^-/- mice.
18	28507796	In summary, our findings reveal a tumor-inhibiting role for LYG1 through promoting the activation, proliferation, and function of CD4⁺ T cells in antitumor immune responses, offering implications for novel tumor immunotherapy.
19	28507796	LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4⁺ T cells.
20	28507796	LYG1 recombinant protein (rhLYG1) could significantly suppress the growth of B16 tumors in WT B6 mice, but not in SCID-beige mice, Rag1^-/- mice, CD4⁺- or CD8⁺ T cell-deleted mice.
21	28507796	It could increase the number of CD4⁺ and CD8⁺ T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes, and spleens, and promote IFNγ production by T cells in tumor-bearing mice.
22	28507796	In vitro experiments demonstrated that rhLYG1 could directly enhance IFNγ secretion by CD4⁺ T cells, but not CD8⁺ T cells.
23	28507796	The tumor-inhibiting effect of LYG1 was eliminated in Ifng^-/- mice.
24	28507796	In summary, our findings reveal a tumor-inhibiting role for LYG1 through promoting the activation, proliferation, and function of CD4⁺ T cells in antitumor immune responses, offering implications for novel tumor immunotherapy.