Ignet

Gene Information

Gene symbol: MDM2

Gene name: Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)

HGNC ID: 6973

Synonyms: HDM2, HDMX, MGC5370

Related Genes

#	Gene Symbol	Number of hits
1	BBC3	1 hits
2	CDK4	1 hits
3	CDKN1A	1 hits
4	DDIT3	1 hits
5	GLI1	1 hits
6	IFNG	1 hits
7	LRP1	1 hits
8	PAK3	1 hits
9	RAP1B	1 hits
10	SLC25A19	1 hits
11	TSPAN31	1 hits

Related Sentences

#	PMID	Sentence
1	27451029	Gene expression analysis of a chosen set of radiation response genes in irradiated PBMC revealed a similar profile for DNA damage response and repair genes including FDXR, XPC, DDB2, and GADD45 in DNC-treated cells compared to IR control.
2	27451029	However, in response to radiation, an altered profile of expression was noticed for CDKN1A (p21), MDM2, IFNG, and BBC3 (PUMA) genes after DNC treatment.
3	10329377	In this region, the MDM2 and IFNG genes were noted as known genes that could be involved in human carcinogenesis.
4	10329377	In this region, the MDM2 and IFNG genes were noted as known genes that could be involved in human carcinogenesis.
5	10329377	Southern blot analysis of genomic DNA of the tumor revealed the amplification of the MDM2 gene together with the fragment locus, but not the IFNG gene.
6	10329377	Southern blot analysis of genomic DNA of the tumor revealed the amplification of the MDM2 gene together with the fragment locus, but not the IFNG gene.
7	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
8	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
9	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
10	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
11	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
12	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
13	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
14	8912848	Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
15	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
16	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
17	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
18	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
19	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
20	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
21	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
22	8912848	The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
23	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
24	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
25	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
26	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
27	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
28	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
29	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
30	8912848	Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
31	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
32	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
33	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
34	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
35	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
36	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
37	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
38	8912848	All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
39	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
40	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
41	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
42	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
43	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
44	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
45	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
46	8912848	These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
47	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
48	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
49	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
50	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
51	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
52	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
53	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
54	8912848	A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
55	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
56	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
57	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
58	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
59	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
60	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
61	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
62	8912848	All amplicons were discontinuous between CDK4/SAS and MDM2.
63	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
64	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
65	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
66	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
67	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
68	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
69	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
70	8912848	Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.