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Gene Information

Gene symbol: MIRN193A

Gene name:

HGNC ID:

Related Genes

# Gene Symbol Number of hits
1 IL12A 1 hits

Related Sentences

# PMID Sentence
1 26589234 Evidence for Epigenetic Regulation of Pro-Inflammatory Cytokines, Interleukin-12 and Interferon Gamma, in Peripheral Blood Mononuclear Cells from PTSD Patients.
2 26589234 While overall DNA methylation level did not differ significantly between control and PTSD, the promoters of several individual genes (e.g., Interferon gamma (IFNG) and Interleukin (IL)-12B) were differentially methylated.
3 26589234 ChIP-seq data revealed that the promoter of IFNG and TBX-21 was associated with the activation marker H3K4me3 in PTSD.
4 26589234 The transcript levels of both IFNG and TBX-21 were higher in PTSD correlating well with the altered methylation patterns.
5 26589234 Knockdown of lysine (K)-specific demethylase 5B (KDM5B), or inhibition of DNA (Cytosine-5-)-methyltransferase 1 (DNMT1) caused up-regulation of IL-12.
6 26589234 Our miRNA microarray identified many downregulated miRNAs in PTSD that are predicted to target IFNG and IL-12.
7 26589234 Consequently, we showed that up-regulation of hsa-miR-193a-5p could decrease the expression of IL-12.