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Gene Information

Gene symbol: MX1

Gene name: myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

HGNC ID: 7532

Synonyms: IFI-78K, MxA

Related Genes

# Gene Symbol Number of hits
1 CCL4 1 hits
2 CX3CL1 1 hits
3 CXCL10 1 hits
4 CXCL11 1 hits
5 CXCL9 1 hits
6 IFI27 1 hits
7 IFI6 1 hits
8 IFIT5 1 hits
9 IFITM5 1 hits
10 IFNA1 1 hits
11 IFNG 1 hits
12 IL12B 1 hits
13 IL13 1 hits
14 IL17D 1 hits
15 IL18 1 hits
16 IL1B 1 hits
17 IL22 1 hits
18 IRF9 1 hits
19 ISG15 1 hits
20 OAS2 1 hits
21 OASL 1 hits
22 RSAD2 1 hits
23 STAT1 1 hits
24 STAT2 1 hits

Related Sentences

# PMID Sentence
1 27071061 HPAI H5N1 virus induced excessive expression of type I IFNs (IFNA and IFNG), cytokines (IL1B, IL18, IL22, IL13, and IL12B), chemokines (CCL4, CCL19, CCL10, and CX3CL1) and IFN stimulated genes (OASL, MX1, RSAD2, IFITM5, IFIT5, GBP 1, and EIF2AK) in lung tissues.
2 15661146 The most noteworthy changes in gene expression mainly affected the transcriptional network regulated by interferons (IFNs), including both IFN-alpha/beta-inducible genes (STAT1, STAT2, ISGF3G/IRF9, IFI27, G1P3, G1P2, OAS2, MX1) and IFN-gamma-inducible genes (CXCL9, CXCL10, CXCL11).
3 15661146 Interesting, upregulation of IFN-alpha/beta-inducible genes (but not IFN-gamma-inducible genes) was independent of histological scores (grade and stage of fibrosis) and HCV characteristics (hepatic HCV mRNA levels and the HCV genotype), and was specific to HCV (as compared to hepatitis B virus (HBV)).
4 15661146 Other genes dysregulated in F1-CH-C, albeit less markedly than IFN-alpha/beta- and IFN-gamma-inducible genes, were mainly involved in the activation of lymphocytes infiltrating the liver (IFNG, TNF, CXCL6, IL6, CCL8, CXCR3, CXCR4, CCR2), cell proliferation (p16/CDKN2A, MKI67, p14/ARF), extracellular matrix remodeling (MMP9, ITGA2), lymphangiogenesis (XLKD1/LYVE), oxidative stress (CYP2E1), and cytoskeleton microtubule organization (STMN2/SCG10).