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Gene Information

Gene symbol: MYCN

Gene name: v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

HGNC ID: 7559

Synonyms: bHLHe37, N-myc

Related Genes

# Gene Symbol Number of hits
1 ERN1 1 hits
2 IL2 1 hits
3 JUN 1 hits
4 MYC 1 hits
5 NMI 1 hits
6 TGFB1 1 hits

Related Sentences

# PMID Sentence
1 24936061 A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
2 24936061 A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
3 24936061 Based on this approach, we identified N-Myc interactor (NMI) as an IRE1α-interacting/modulator protein in rodent and human pancreatic beta cells.
4 24936061 Based on this approach, we identified N-Myc interactor (NMI) as an IRE1α-interacting/modulator protein in rodent and human pancreatic beta cells.
5 24936061 An increased expression of NMI was detected in islets from nonobese diabetic mice with insulitis and in rodent or human beta cells exposed in vitro to the pro-inflammatory cytokines interleukin-1β and interferon-γ.
6 24936061 An increased expression of NMI was detected in islets from nonobese diabetic mice with insulitis and in rodent or human beta cells exposed in vitro to the pro-inflammatory cytokines interleukin-1β and interferon-γ.
7 24936061 Detailed mechanistic studies demonstrated that NMI negatively modulates IRE1α-dependent activation of JNK and apoptosis in rodent and human pancreatic beta cells.
8 24936061 Detailed mechanistic studies demonstrated that NMI negatively modulates IRE1α-dependent activation of JNK and apoptosis in rodent and human pancreatic beta cells.
9 24936061 In conclusion, by using a combined omics approach, we identified NMI induction as a novel negative feedback mechanism that decreases IRE1α-dependent activation of JNK and apoptosis in cytokine-exposed beta cells
10 24936061 In conclusion, by using a combined omics approach, we identified NMI induction as a novel negative feedback mechanism that decreases IRE1α-dependent activation of JNK and apoptosis in cytokine-exposed beta cells
11 23071669 These included five that were common to both ages (TNF, HNF4A, IL15, Progesterone, and YWHAZ), and others that were unique to 2 weeks (e.g.
12 23071669 MYC/MYCN, TGFB1, and IL2) and to 4 weeks (e.g.
13 23071669 IFNG, beta-estradiol, p53, NFKB, AKT, PRKCA, IL12, and HLA-C).
14 23071669 Based on the literature, genes that may play a role in regulating metabolic pathways at 2 weeks include Myc and HNF4A, and at 4 weeks, beta-estradiol, p53, Akt, HNF4A and AR.