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Gene Information
Gene symbol: MYLK
Gene name: myosin light chain kinase
HGNC ID: 7590
Synonyms: MLCK, smMLCK, MYLK1, MLCK1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ANGPT2 | 1 hits |
| 2 | CD14 | 1 hits |
| 3 | FCN2 | 1 hits |
| 4 | HMGB1 | 1 hits |
| 5 | HSPA1B | 1 hits |
| 6 | HSPA1L | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | IL10 | 1 hits |
| 9 | IL17F | 1 hits |
| 10 | IL18 | 1 hits |
| 11 | IL1A | 1 hits |
| 12 | IL1B | 1 hits |
| 13 | IL1RN | 1 hits |
| 14 | IL4 | 1 hits |
| 15 | IL6 | 1 hits |
| 16 | IL8 | 1 hits |
| 17 | LTA | 1 hits |
| 18 | MASP2 | 1 hits |
| 19 | MBL2 | 1 hits |
| 20 | MYH14 | 1 hits |
| 21 | NR1I2 | 1 hits |
| 22 | SERPINE1 | 1 hits |
| 23 | TJP1 | 1 hits |
| 24 | TLR1 | 1 hits |
| 25 | TLR2 | 1 hits |
| 26 | TLR4 | 1 hits |
| 27 | TLR9 | 1 hits |
| 28 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 26473437 | The following genes have been studied in populations of trauma patients: CD14, HMGB1, IFNG, IL1A, IL1B, IL1RN, IL4, IL6, IL8, IL10, IL17F, IL18, MBL2, MASP2, FCN2, TLR1, TLR2, TLR4, TLR9, TNF, LTA, GR, MYLK, NLRP3, PRDX6, RAGE, HSPA1B, HSPA1L, HSP90, SERPINE1, IRAK1, IRAK3, VEGFA, LY96, ANGPT2, LBP, MicroRNA, and mtDNA. |
| 2 | 15194744 | PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways. |
| 3 | 15194744 | We further investigated the possible involvement of interferon gamma (IFN-gamma) and calmodulin-dependent activation of myosin light chain kinase (MLCK), and alterations of zonula occludens-1 (ZO-1) localization in PAR(2)-induced responses. |
| 4 | 15194744 | Western blotting showed phosphorylation of mucosal myosin light chain (MLC) expression after both doses of SLIGRL. |
| 5 | 15194744 | Finally, we have shown that direct activation of PAR(2) on enterocytes is responsible for increased permeability and ZO-1 disruption. |
| 6 | 15194744 | The resulting tight junction opening does not depend upon IFN-gamma secretion, while the increased permeability in response to the high dose of PAR(2) agonist involves IFN-gamma secretion. |