Ignet

Gene Information

Gene symbol: NOS1

Gene name: nitric oxide synthase 1 (neuronal)

HGNC ID: 7872

Synonyms: nNOS

Related Genes

#	Gene Symbol	Number of hits
1	ADAM33	1 hits
2	AICDA	1 hits
3	CLCA1	1 hits
4	DPP10	1 hits
5	GSTP1	1 hits
6	HLA-G	1 hits
7	IFNG	1 hits
8	IL1RN	1 hits
9	MS4A2	1 hits
10	NOS2A	1 hits
11	NPSR1	1 hits
12	PHF11	1 hits
13	PTGDR	1 hits
14	SERPINA3	1 hits
15	STAT6	1 hits
16	TNF	1 hits

Related Sentences

#	PMID	Sentence
1	20811799	IFNG-inducible KYN/pteridines inflammation cascade is characterized by up-regulation of nitric oxide synthase (NOS) activity (induced by KYN) and decreased formation of NOS cofactor, BH4, that results in uncoupling of NOS that shifting arginine from NO to superoxide anion production.
2	20811799	IFNG-induced up-regulation of indoleamine 2,3-dioxygenase (IDO), rate-limiting enzyme of TRY-KYN pathway, decreases TRY conversion into serotonin (substrate of antidepressant effect) and increases production of KYN associated with diabetes [xanthurenic acid (XA)], anxiety (KYN), psychoses and cognitive impairment (kynurenic acid).
3	20811799	In addition to literature data on KYN/TRY ratio (IDO activity index), we observe neopterin levels (index of activity of rate-limiting enzyme of guanine-BH4 pathway) to be higher in carriers of high (T) than of low (A) producers alleles; and to correlate with AAMPD markers (e.g., insulin resistance, body mass index, mortality risk), and with IFN-alpha-induced depression in hepatitis C patients.
4	15741670	Candidate gene and genome wide studies have localized genetic regions involved in the disease, such as the A1AR and CLCA1 genes (chromosome 1), IL-1RN and DPP10 (2q14), HLA-G and TNF-a (6p21), GPRA (7p14), FceRI and GSTP1 (11q13), NOS1, IFNG, STAT6, VDR, and other genes (12q13-26), PHF11 and flanking genes (13q14), AACT and PTGDR (14q), and ADAM33 (20p13).
5	14767694	Chromosome 12 genes that showed association with the disease in at least one report include: the signal transducer and activator of transcription 6 gene ( STAT6), the nitrogen oxide synthetase 1 gene ( NOS1), the interferon gamma gene ( IFNG), and the activation-induced cytidine deaminase gene ( AICDA).
6	14767694	Chromosome 12 genes that showed association with the disease in at least one report include: the signal transducer and activator of transcription 6 gene ( STAT6), the nitrogen oxide synthetase 1 gene ( NOS1), the interferon gamma gene ( IFNG), and the activation-induced cytidine deaminase gene ( AICDA).
7	14767694	Chromosome 12 genes that showed association with the disease in at least one report include: the signal transducer and activator of transcription 6 gene ( STAT6), the nitrogen oxide synthetase 1 gene ( NOS1), the interferon gamma gene ( IFNG), and the activation-induced cytidine deaminase gene ( AICDA).
8	14767694	Chromosome 12 genes that showed association with the disease in at least one report include: the signal transducer and activator of transcription 6 gene ( STAT6), the nitrogen oxide synthetase 1 gene ( NOS1), the interferon gamma gene ( IFNG), and the activation-induced cytidine deaminase gene ( AICDA).
9	14767694	To investigate association between chromosome 12 candidate genes and asthma, distributions of alleles and genotypes of repeat polymorphisms of STAT6, NOS1, and IFNG were compared between controls and patients.
10	14767694	To investigate association between chromosome 12 candidate genes and asthma, distributions of alleles and genotypes of repeat polymorphisms of STAT6, NOS1, and IFNG were compared between controls and patients.
11	14767694	To investigate association between chromosome 12 candidate genes and asthma, distributions of alleles and genotypes of repeat polymorphisms of STAT6, NOS1, and IFNG were compared between controls and patients.
12	14767694	To investigate association between chromosome 12 candidate genes and asthma, distributions of alleles and genotypes of repeat polymorphisms of STAT6, NOS1, and IFNG were compared between controls and patients.
13	14767694	The NOS1 intron 2 GT repeat and STAT6 exon 1 GT repeat were associated with asthma.
14	14767694	The NOS1 intron 2 GT repeat and STAT6 exon 1 GT repeat were associated with asthma.
15	14767694	The NOS1 intron 2 GT repeat and STAT6 exon 1 GT repeat were associated with asthma.
16	14767694	The NOS1 intron 2 GT repeat and STAT6 exon 1 GT repeat were associated with asthma.
17	14767694	Neither the IFNG intron 1 CA repeat nor 465C/T of AICDA showed any association with asthma.
18	14767694	Neither the IFNG intron 1 CA repeat nor 465C/T of AICDA showed any association with asthma.
19	14767694	Neither the IFNG intron 1 CA repeat nor 465C/T of AICDA showed any association with asthma.
20	14767694	Neither the IFNG intron 1 CA repeat nor 465C/T of AICDA showed any association with asthma.
21	14767694	Our results suggest that NOS1 and STAT6 are asthma-susceptibility genes and that chromosome region 12q24.23-q24.33 contains other susceptibility gene(s).
22	14767694	Our results suggest that NOS1 and STAT6 are asthma-susceptibility genes and that chromosome region 12q24.23-q24.33 contains other susceptibility gene(s).
23	14767694	Our results suggest that NOS1 and STAT6 are asthma-susceptibility genes and that chromosome region 12q24.23-q24.33 contains other susceptibility gene(s).
24	14767694	Our results suggest that NOS1 and STAT6 are asthma-susceptibility genes and that chromosome region 12q24.23-q24.33 contains other susceptibility gene(s).