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Gene Information
Gene symbol: NOX5
Gene name: NADPH oxidase, EF-hand calcium binding domain 5
HGNC ID: 14874
Synonyms: NOX5A, NOX5B
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYBB | 1 hits |
| 2 | NOX1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 28760732 | The NADPH oxidase of myeloid cells, NOX2, generates reactive oxygen species (ROS) to eliminate pathogens and malignant cells. |
| 2 | 24368122 | These stimuli can also induce IFN-γ-pretreated neutrophils to release reactive oxygen species (ROS), such as superoxide anion, hydrogen peroxide and hypochlorous acid, as well as granule lysosomal enzymes and the pro-inflammatory cytokines TNF-α and IL-6. |
| 3 | 24368122 | The enhancing effect of IFN-γ on the respiratory burst was found to be associated with up-regulation of the gp91(phox) and p47(phox) subunits of NADPH oxidase, as measured by their mRNA levels. |
| 4 | 23918204 | In this study we investigated ROS production in human astrocytes stimulated with interleukin (IL)-1β and interferon (IFN)-γ and its potential harmful effects. |
| 5 | 23918204 | One of the sources of ROS in IL-1β-activated astrocytes was from increased superoxide production in mitochondria accompanied by enhanced manganese superoxide dismutase and inhibited catalase expression. |
| 6 | 23918204 | NADPH oxidase (NOX) may also contribute to ROS production as astrocytes express NOX isoforms. |