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Gene Information
Gene symbol: OGT
Gene name: O-linked N-acetylglucosamine (GlcNAc) transferase
HGNC ID: 8127
Synonyms: O-GLCNAC, HRNT1, MGC22921, FLJ23071
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | REL | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23982206 | Activation of the transcriptional function of the NF-κB protein c-Rel by O-GlcNAc glycosylation. |
| 2 | 23982206 | Blocking the O-GlcNAcylation of this residue abrogated c-Rel-mediated expression of the cytokine-encoding genes IL2, IFNG, and CSF2 in response to T cell receptor (TCR) activation, whereas increasing the extent of O-GlcNAcylation of cellular proteins enhanced the expression of these genes. |
| 3 | 23982206 | TCR- or tumor necrosis factor (TNF)-induced expression of other NF-κB target genes, such as NFKBIA (which encodes IκBα) and TNFAIP3 (which encodes A20), occurred independently of the O-GlcNAcylation of c-Rel. |