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Gene Information
Gene symbol: P2RX7
Gene name: purinergic receptor P2X, ligand-gated ion channel, 7
HGNC ID: 8537
Synonyms: P2X7, MGC20089
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
28798231
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P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy.
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2 |
28798231
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In immune cells, P2X7R activation induces the production of proinflammatory cytokines, including IL-1β and IL-18, by inducing the oligomerization of the multiprotein complex NLRP3-type inflammasome.
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