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Gene Information
Gene symbol: PAK3
Gene name: p21 protein (Cdc42/Rac)-activated kinase 3
HGNC ID: 8592
Synonyms: hPAK3, bPAK
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AFP | 1 hits |
| 2 | BBC3 | 1 hits |
| 3 | CD4 | 1 hits |
| 4 | CDKN1A | 1 hits |
| 5 | CXCL14 | 1 hits |
| 6 | DNMT1 | 1 hits |
| 7 | FGF2 | 1 hits |
| 8 | IFNG | 1 hits |
| 9 | IL1RN | 1 hits |
| 10 | IL2 | 1 hits |
| 11 | MDM2 | 1 hits |
| 12 | NUDT6 | 1 hits |
| 13 | RETN | 1 hits |
| 14 | SELL | 1 hits |
| 15 | SLC25A19 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 27451029 | Gene expression analysis of a chosen set of radiation response genes in irradiated PBMC revealed a similar profile for DNA damage response and repair genes including FDXR, XPC, DDB2, and GADD45 in DNC-treated cells compared to IR control. |
| 2 | 27451029 | However, in response to radiation, an altered profile of expression was noticed for CDKN1A (p21), MDM2, IFNG, and BBC3 (PUMA) genes after DNC treatment. |
| 3 | 22407948 | Previous studies have shown that short-term (4 weeks) or chronic (32 weeks) exposure to trichloroethylene (TCE) in drinking water of female MRL+/+ mice generated CD4(+) T cells that secreted increased levels of interferon (IFN)-γ and expressed an activated (CD44(hi)CD62L(lo)) phenotype. |
| 4 | 22407948 | Previous studies have shown that short-term (4 weeks) or chronic (32 weeks) exposure to trichloroethylene (TCE) in drinking water of female MRL+/+ mice generated CD4(+) T cells that secreted increased levels of interferon (IFN)-γ and expressed an activated (CD44(hi)CD62L(lo)) phenotype. |
| 5 | 22407948 | Also observed was an increase in the expression of Dnmt1 (DNA methyltransferase-1) and decreased expression of several genes known to be downregulated by DNA methylation, namely Ifng, Il2, and Cdkn1a. |
| 6 | 22407948 | Also observed was an increase in the expression of Dnmt1 (DNA methyltransferase-1) and decreased expression of several genes known to be downregulated by DNA methylation, namely Ifng, Il2, and Cdkn1a. |
| 7 | 22407948 | CD4(+) T cells from a second study in which MRL+/+ mice were treated for 17 weeks with TCE showed a similar increase in Iap and decrease in Cdkn1a. |
| 8 | 22407948 | CD4(+) T cells from a second study in which MRL+/+ mice were treated for 17 weeks with TCE showed a similar increase in Iap and decrease in Cdkn1a. |
| 9 | 19578489 | We identified 7 proteins that significantly differentiate HCC patients from hepatitis patients (p < 0.05) (AFP, CTNNB, CSF1, SELL, IGFBP6, IL6R, and VCAM1). |
| 10 | 19578489 | Importantly, we also identified 8 proteins that significantly differentiate HCC patients with 'normal' levels of AFP (< 20 ng/ml) from hepatitis patients (p < 0.05) (IL1RN, IFNG, CDKN1A, RETN, CXCL14, CTNNB, FGF2, and SELL). |