Ignet

Gene Information

Gene symbol: PIK3CG

Gene name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

HGNC ID: 8978

Related Genes

#	Gene Symbol	Number of hits
1	LAT	1 hits
2	PIK3R1	1 hits
3	PTK2B	1 hits
4	TRA	1 hits
5	TYK2	1 hits

Related Sentences

#	PMID	Sentence
1	25387834	Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.
2	25387834	Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.
3	25387834	Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.
4	25387834	Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.
5	25387834	Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.
6	25387834	We have previously shown that Pyk2 is activated downstream of the TCR in a PI3K-independent manner.
7	25387834	We have previously shown that Pyk2 is activated downstream of the TCR in a PI3K-independent manner.
8	25387834	We have previously shown that Pyk2 is activated downstream of the TCR in a PI3K-independent manner.
9	25387834	We have previously shown that Pyk2 is activated downstream of the TCR in a PI3K-independent manner.
10	25387834	We have previously shown that Pyk2 is activated downstream of the TCR in a PI3K-independent manner.
11	25387834	We observed that Pyk2 localized with the p85 regulatory subunit of PI3K at the LAT complex and that PI3K-dependent signaling was impaired in Pyk2-deficient T cells.
12	25387834	We observed that Pyk2 localized with the p85 regulatory subunit of PI3K at the LAT complex and that PI3K-dependent signaling was impaired in Pyk2-deficient T cells.
13	25387834	We observed that Pyk2 localized with the p85 regulatory subunit of PI3K at the LAT complex and that PI3K-dependent signaling was impaired in Pyk2-deficient T cells.
14	25387834	We observed that Pyk2 localized with the p85 regulatory subunit of PI3K at the LAT complex and that PI3K-dependent signaling was impaired in Pyk2-deficient T cells.
15	25387834	We observed that Pyk2 localized with the p85 regulatory subunit of PI3K at the LAT complex and that PI3K-dependent signaling was impaired in Pyk2-deficient T cells.
16	25387834	Likewise, functions downstream of PI3K, including IFN-γ production and proliferation, were also suppressed in human T cells deficient in Pyk2.
17	25387834	Likewise, functions downstream of PI3K, including IFN-γ production and proliferation, were also suppressed in human T cells deficient in Pyk2.
18	25387834	Likewise, functions downstream of PI3K, including IFN-γ production and proliferation, were also suppressed in human T cells deficient in Pyk2.
19	25387834	Likewise, functions downstream of PI3K, including IFN-γ production and proliferation, were also suppressed in human T cells deficient in Pyk2.
20	25387834	Likewise, functions downstream of PI3K, including IFN-γ production and proliferation, were also suppressed in human T cells deficient in Pyk2.
21	25387834	Collectively, these data demonstrate that Pyk2 is a critical regulator of PI3K function downstream of the TCR.
22	25387834	Collectively, these data demonstrate that Pyk2 is a critical regulator of PI3K function downstream of the TCR.
23	25387834	Collectively, these data demonstrate that Pyk2 is a critical regulator of PI3K function downstream of the TCR.
24	25387834	Collectively, these data demonstrate that Pyk2 is a critical regulator of PI3K function downstream of the TCR.
25	25387834	Collectively, these data demonstrate that Pyk2 is a critical regulator of PI3K function downstream of the TCR.