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Gene Information

Gene symbol: PTPRC

Gene name: protein tyrosine phosphatase, receptor type, C

HGNC ID: 9666

Synonyms: LCA, T200, GP180

Related Genes

# Gene Symbol Number of hits
1 BTK 1 hits
2 CD22 1 hits
3 CD4 1 hits
4 CD8A 1 hits
5 FCRL4 1 hits
6 FOXP3 1 hits
7 FYN 1 hits
8 HLX 1 hits
9 IL2RA 1 hits
10 IRF1 1 hits
11 LAX1 1 hits
12 LYN 1 hits
13 NFAM1 1 hits
14 RPL32 1 hits
15 STAT1 1 hits
16 SYK 1 hits

Related Sentences

# PMID Sentence
1 25411767 The results showed that PE patients exhibited significantly increased expression levels of the B‑cell receptor genes LYN, CD22, SYK, BTK, PTPRC and NFAM1, whereas expression levels of FYN, FCRL4 and LAX1 were significantly decreased compared to those of the control group.
2 25411767 Expression levels of T‑cell‑dependent B‑cell‑activation genes, including EMR2, TNFSF9, CD86, ICOSLG, CD37 and CD97, were significantly upregulated in PE patients, whereas SPN mRNA expression was significantly downregulated compared with those of the control group.
3 25411767 LILRA1 and TLR9 T cell‑independent B‑cell activation mRNAs were significantly upregulated in PE patients compared with those of the control group.
4 25411767 In addition, the expression levels of B‑cell‑activation regulator genes, including CR1, LILRB4 and VAV1, were significantly increased, whereas SLAMF7 expression levels were significantly decreased in PE patients compared with those of the control group.
5 25411767 Furthermore, the expression levels of B‑cell‑activation‑associated cytokine genes demonstrated a significant upregulation of LTA and IL10 and downregulation of L1A, IFNA5, IFNA6, IFNA8, IFNA14, IL2, IL13 and IFNG in PE patients compared to those of the control group.
6 25403334 Our results showed that serum levels of IL-2, IL-10, and IFN-γ in COPD patients before treatment are significantly higher than levels in non-COPD controls (p < 0.05).
7 25403334 The effects of Rhodiola treatment on COPD patients were shown to decrease the IFN-γ concentration and CD8(+) count but increase the expressions of CD4(+) CD25(+) FOXP3(+) and CD4(+) CD25(+) CD45(+) FOXP3(+) in the blood significantly (p < 0.05).
8 15183000 This publication describes the cloning of full or partial length sequences for pig TBX21 (T-bet), MYD88, ICSBP1, CD8A (CD8alpha), CD8B (CD8beta), and CD28 cDNAs.
9 15183000 Real-time PCR assays have been developed for the relative quantitation of these products as well as previously characterized transcripts that encode exon A-containing CD45, HLX1, IRF1, STAT1 and RPL32.
10 15183000 When used for examining temporal immune gene expression in the liver of Toxoplasma gondii infected pigs, the positive regulators of Th1 responses, IRF1, MYD88, and STAT1, were found to be expressed prior to the simultaneous upregulation of interferon gamma (IFNG), HLX1 and TBX21 gene expression.
11 15183000 In contrast, in the mesenteric lymph node (MLN), only expression of IRF1 and IFNG was significantly upregulated.