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Gene Information
Gene symbol: PVR
Gene name: poliovirus receptor
HGNC ID: 9705
Synonyms: CD155, HVED, Necl-5, NECL5, Tage4
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
24817116
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TIGIT receptor/poliovirus receptor (PVR) ligand engagement signaling inhibits cytotoxicity mediated by NK and CD8(+) T cells.
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2 |
24817116
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We identified a novel adaptor β-arrestin 2 that associates with phosphorylated TIGIT for further recruitment of SHIP1 (SH2-containing inositol phosphatase 1) through the ITT-like motif.
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3 |
24817116
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Importantly, SHIP1, but not other phosphatases, impairs the TNF receptor-associated factor 6 (TRAF6) autoubiquitination to abolish NF-κB activation, leading to suppression of IFN-γ production in NK cells.
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