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Gene Information
Gene symbol: SH3GLB1
Gene name: SH3-domain GRB2-like endophilin B1
HGNC ID: 10833
Synonyms: CGI-61, KIAA0491, Bif-1, PPP1R70
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BAX | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | IRGM | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25619828 | IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy. |
| 2 | 25619828 | In the current study, we showed that immunity-related GTPase family member 1 (mouse: Irgm1; human: IRGM) is essential for IFNg-mediated regulation of tumor cell growth in melanoma. |
| 3 | 25619828 | IFNg and starvation synergistically induced Irgm1 expression in melanoma B16 cells. |
| 4 | 25619828 | In vitro, knockdown endogenous or IFNg-induced Irgm1 significantly decreases the proliferation and increases apoptosis of B16 cells. |
| 5 | 25619828 | In addition, suppressing Irgm1 decreased the IFNg/starvation-induced autophagy, while overexpressing Irgm1 significantly increased autophagy and rescued starvation-challenged cells. |
| 6 | 25619828 | Moreover, IFNg and starvation-induced the co-localization of Irgm1 with Bax-interacting factor 1 (Bif-1). |
| 7 | 25619828 | IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy. |
| 8 | 25619828 | In the current study, we showed that immunity-related GTPase family member 1 (mouse: Irgm1; human: IRGM) is essential for IFNg-mediated regulation of tumor cell growth in melanoma. |
| 9 | 25619828 | IFNg and starvation synergistically induced Irgm1 expression in melanoma B16 cells. |
| 10 | 25619828 | In vitro, knockdown endogenous or IFNg-induced Irgm1 significantly decreases the proliferation and increases apoptosis of B16 cells. |
| 11 | 25619828 | In addition, suppressing Irgm1 decreased the IFNg/starvation-induced autophagy, while overexpressing Irgm1 significantly increased autophagy and rescued starvation-challenged cells. |
| 12 | 25619828 | Moreover, IFNg and starvation-induced the co-localization of Irgm1 with Bax-interacting factor 1 (Bif-1). |