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Gene Information
Gene symbol: SOD2
Gene name: superoxide dismutase 2, mitochondrial
HGNC ID: 11180
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ABL1 | 1 hits |
| 2 | CAT | 1 hits |
| 3 | IFNG | 1 hits |
| 4 | IL10 | 1 hits |
| 5 | IL1B | 1 hits |
| 6 | IL6 | 1 hits |
| 7 | LTA | 1 hits |
| 8 | NOD2 | 1 hits |
| 9 | TLR1 | 1 hits |
| 10 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 28715406 | Genetic polymorphisms of the IL6 and NOD2 genes are risk factors for inflammatory reactions in leprosy. |
| 2 | 28715406 | From the 15 single nucleotide polymorphisms (SNPs) at the 8 candidate genes genotyped (TNF/LTA, IFNG, IL10, TLR1, NOD2, SOD2, and IL6) we observed statistically different survival curves for rs751271 at the NOD2 and rs2069845 at the IL6 genes (log-rank p-values = 0.002 and 0.023, respectively), suggesting an influence on the amount of time before developing leprosy reactions. |
| 3 | 28715406 | Cox models showed associations between the SNPs rs751271 at NOD2 and rs2069845 at IL6 with leprosy reactions (HRGT = 0.45, p = 0.002; HRAG = 1.88, p = 0.0008, respectively). |
| 4 | 28715406 | Finally, IL-6 and IFN-γ levels were confirmed as high, while IL-10 titers were low in the sera of reactional patients. |
| 5 | 28715406 | From the results, we conclude that SNPs at the NOD2 and IL6 genes are associated with leprosy reactions as an outcome. |
| 6 | 23918204 | In this study we investigated ROS production in human astrocytes stimulated with interleukin (IL)-1β and interferon (IFN)-γ and its potential harmful effects. |
| 7 | 23918204 | One of the sources of ROS in IL-1β-activated astrocytes was from increased superoxide production in mitochondria accompanied by enhanced manganese superoxide dismutase and inhibited catalase expression. |
| 8 | 23918204 | NADPH oxidase (NOX) may also contribute to ROS production as astrocytes express NOX isoforms. |
| 9 | 11121210 | Radiation of the esophagus of C3H/HeNsd mice with 35 or 37 Gy of 6 MV X rays induces significantly increased RNA transcription for interleukin 1 (Il1), tumor necrosis factor alpha (Tnf), interferon gamma inducing factor (Ifngr), and interferon gamma (Ifng). |
| 10 | 11121210 | An equivalent therapeutic plasmid weight of 10 microgram ALP plasmid in the same 500 microliter of liposomes, correlated to around 52-60% of alkaline phosphatase-positive cells in the squamous layer of the esophagus at 24 h. |
| 11 | 11121210 | Mice with orthotopic thoracic tumors composed of 32D-v-abl cells that received intraesophageal SOD2-PL treatment showed transgenic mRNA in the esophagus at 24 h, but no detectable human SOD2 transgene mRNA in explanted tumors by nested RT-PCR. |