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Gene Information
Gene symbol: SOX2
Gene name: SRY (sex determining region Y)-box 2
HGNC ID: 11195
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IGF1 | 1 hits |
| 2 | INS | 1 hits |
| 3 | KLF4 | 1 hits |
| 4 | MYC | 1 hits |
| 5 | NANOG | 1 hits |
| 6 | POU5F1 | 1 hits |
| 7 | TGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 26619160 | Pluripotency genes including Oct-4, Sox-2, and Nanog as well as proliferation-associated immunomodulatory cytokines such as insulin-like growth factor 1 (IGF-1) and transforming growth factor-β (TGF-β) expression were evaluated using real-time PCR. |
| 2 | 21734265 | During reprogramming of porcine mesenchymal cells with a four-factor (POU5F1/SOX2/KLF4/MYC) mixture of vectors, a fraction of the colonies had an atypical phenotype and arose earlier than the recognizable porcine induced pluripotent stem (iPS) cell colonies. |
| 3 | 21734265 | Relative to gene expression of the iPS cells, there was up-regulation of genes for transcription factors associated with trophoblast (TR) lineage emergence, e.g., GATA2, PPARG, MSX2, DLX3, HAND1, GCM1, CDX2, ID2, ELF5, TCFAP2C, and TEAD4 and for genes required for synthesis of products more typical of differentiated TR, such as steroids (HSD17B1, CYP11A1, and STAR), pregnancy-associated glycoproteins (PAG6), and select cytokines (IFND, IFNG, and IL1B). |