Ignet

Gene Information

Gene symbol: THM

Gene name: thymoma

HGNC ID: 11792

Related Genes

#	Gene Symbol	Number of hits
1	EOMES	1 hits
2	IFNG	1 hits
3	TBX21	1 hits

Related Sentences

#	PMID	Sentence
1	26749212	Eomesodermin promotes interferon-γ expression and binds to multiple conserved noncoding sequences across the Ifng locus in mouse thymoma cell lines.
2	26749212	Eomesodermin promotes interferon-γ expression and binds to multiple conserved noncoding sequences across the Ifng locus in mouse thymoma cell lines.
3	26749212	The T-box transcription factors T-bet and eomesodermin (Eomes) have been shown to regulate the lineage-specific expression of interferon-γ (IFN-γ).
4	26749212	The T-box transcription factors T-bet and eomesodermin (Eomes) have been shown to regulate the lineage-specific expression of interferon-γ (IFN-γ).
5	26749212	However, in contrast to T-bet, the role of Eomes in the expression of IFN-γ remains unclear.
6	26749212	However, in contrast to T-bet, the role of Eomes in the expression of IFN-γ remains unclear.
7	26749212	In this study, we investigated the Eomes-dependent expression of IFN-γ in the mouse thymoma BW5147 and EL4 cells, which do not express T-bet or Eomes.
8	26749212	In this study, we investigated the Eomes-dependent expression of IFN-γ in the mouse thymoma BW5147 and EL4 cells, which do not express T-bet or Eomes.
9	26749212	In BW5147 cells, Eomes augmented luciferase activity driven by the Ifng promoter encoding from -2500 to +113 bp; however, it was not increased by a stimulation with PMA and IM.
10	26749212	In BW5147 cells, Eomes augmented luciferase activity driven by the Ifng promoter encoding from -2500 to +113 bp; however, it was not increased by a stimulation with PMA and IM.
11	26749212	A chromatin immunoprecipitation assay showed that Eomes bound to the Ifng promoter and conserved noncoding sequence (CNS) -22 kb across the Ifng locus with high efficacy in BW5147 cells.
12	26749212	A chromatin immunoprecipitation assay showed that Eomes bound to the Ifng promoter and conserved noncoding sequence (CNS) -22 kb across the Ifng locus with high efficacy in BW5147 cells.
13	26749212	Moreover, Eomes increased permissive histone modifications in the Ifng promoter and multiple CNSs.
14	26749212	Moreover, Eomes increased permissive histone modifications in the Ifng promoter and multiple CNSs.
15	26749212	These results indicated that Eomes bound to the Ifng promoter and multiple CNSs in stimulation-dependent and stimulation-independent manners.
16	26749212	These results indicated that Eomes bound to the Ifng promoter and multiple CNSs in stimulation-dependent and stimulation-independent manners.
17	17509455	Polymorphisms of interferon-gamma, interleukin-10, and interleukin-12 genes in myasthenia gravis.
18	17509455	To assess the involvement of polymorphisms in genetic susceptibility to myasthenia gravis (MG), this study analyzed four polymorphisms of interferon (IFN)-gamma, interleukin (IL)-10, and IL-12 genes in 115 patients and 204 healthy controls (HC).
19	17509455	IFNG +874T carriers were less frequent in MG, in patients with anti-acetylcholine receptor (AChR) (63%) and anti-titin (56.2%) antibodies compared with HC (p = 0.01 for all, OR: 0.5, 0.5, and 0.4, respectively).
20	17509455	The presence of thymoma was also associated with lower frequency of IFNG +874T allele (p = 0.018, OR = 0.34).