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Gene Information
Gene symbol: TJP1
Gene name: tight junction protein 1
HGNC ID: 11827
Synonyms: ZO-1, MGC133289, DKFZp686M05161
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IFNG | 1 hits |
| 2 | IL17A | 1 hits |
| 3 | IL17D | 1 hits |
| 4 | IL26 | 1 hits |
| 5 | MYH14 | 1 hits |
| 6 | MYLK | 1 hits |
| 7 | NR1I2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 26903715 | In contrast, the Th17 cytokines IL-17, IL-22, and IL-26 showed a significant disruption of the epithelial barrier, evidenced by a loss of TEER, increased paracellular permeability of FITC-dextrans, and discontinuous ZO-1 immunolocalisation. |
| 2 | 15194744 | PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways. |
| 3 | 15194744 | PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways. |
| 4 | 15194744 | We further investigated the possible involvement of interferon gamma (IFN-gamma) and calmodulin-dependent activation of myosin light chain kinase (MLCK), and alterations of zonula occludens-1 (ZO-1) localization in PAR(2)-induced responses. |
| 5 | 15194744 | We further investigated the possible involvement of interferon gamma (IFN-gamma) and calmodulin-dependent activation of myosin light chain kinase (MLCK), and alterations of zonula occludens-1 (ZO-1) localization in PAR(2)-induced responses. |
| 6 | 15194744 | Western blotting showed phosphorylation of mucosal myosin light chain (MLC) expression after both doses of SLIGRL. |
| 7 | 15194744 | Western blotting showed phosphorylation of mucosal myosin light chain (MLC) expression after both doses of SLIGRL. |
| 8 | 15194744 | Finally, we have shown that direct activation of PAR(2) on enterocytes is responsible for increased permeability and ZO-1 disruption. |
| 9 | 15194744 | Finally, we have shown that direct activation of PAR(2) on enterocytes is responsible for increased permeability and ZO-1 disruption. |
| 10 | 15194744 | The resulting tight junction opening does not depend upon IFN-gamma secretion, while the increased permeability in response to the high dose of PAR(2) agonist involves IFN-gamma secretion. |
| 11 | 15194744 | The resulting tight junction opening does not depend upon IFN-gamma secretion, while the increased permeability in response to the high dose of PAR(2) agonist involves IFN-gamma secretion. |