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Gene Information
Gene symbol: ASF1A
Gene name: ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
HGNC ID: 20995
Synonyms: DKFZP547E2110, CIA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | COL1A1 | 1 hits |
| 2 | TNFRSF11B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23613752 | Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase. |
| 2 | 23613752 | C57BL/6 mice are known to be resistant to the development of collagen-induced arthritis (CIA). |
| 3 | 23613752 | Also, production of IL-17 by the splenocytes of the IFN-γ KO mice was increased when cultured with type II collagen. |
| 4 | 23613752 | The proportion of CD44(high)CD62L(low) memory-like T cells were elevated in the spleen, draining lymph node and mesenteric lymph node of IFN-γ KO CIA mice. |
| 5 | 23613752 | Meanwhile, CD44(low)CD62L(high) naïve T cells were increased in IFN-γ and IL-17 double KO CIA mice. |
| 6 | 23613752 | When Th17 polarized CD4+ T cells of IFN-γ KO mice were co-cultured with their own antigen presenting cells (APCs), a greater increase in IL-17 production was observed than in co-culture of the cells from wild type mice. |
| 7 | 24222748 | Local gene transfer of OPG prevents joint damage and disease progression in collagen-induced arthritis. |
| 8 | 24222748 | This study examined the influence of osteoprotegerin (OPG) gene transfer on a murine collagen-induced arthritis model. |
| 9 | 24222748 | MicroCT data suggested significant protection against subchondral bone mineral density changes in OPG treated CIA mice. |
| 10 | 24222748 | Interestingly, mRNA expressions of IFN-g and MMP3 were noticeably diminished following OPG gene transfer. |
| 11 | 24222748 | Overall, gene transfer of OPG effectively inhibited the arthritis-associated periarticular bone erosion and preserved the architecture of arthritic joints, and the study provides evidence that the cartilage protection of the OPG gene therapy may be associated with the down-regulation of MMP3 expression. |