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Gene Information
Gene symbol: CD38
Gene name: CD38 molecule
HGNC ID: 1667
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD34 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | CSF2 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | IL10 | 1 hits |
| 6 | IL2 | 1 hits |
| 7 | IL4 | 1 hits |
| 8 | IL5 | 1 hits |
| 9 | LAT | 1 hits |
| 10 | PECAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11259373 | Human CD38 and its ligand CD31 define a unique lamina propria T lymphocyte signaling pathway. |
| 2 | 11259373 | Results are as follows: 1) LP T cells express an enzymatically active form of CD38, characterized by a modified ratio between cyclase and hydrolase functions; 2) LP T cells do not mobilize Ca2+ upon CD38 ligation, as seen in PB T cells (this condition is due to a lack in activation of PLC- g, constantly observed in PB T lymphocytes); 3) The early steps of CD38 signaling involve activation of lck, syk, and LAT; 4) Late events include synthesis and release of IL-2, IL-4, IL-5, IL-10, IFN-g and GM-CSF; 5) The uniqueness of the CD38 pathway in LP T cells is not caused by impaired interactions with the CD31 ligand. |
| 3 | 11259373 | Human CD38 and its ligand CD31 define a unique lamina propria T lymphocyte signaling pathway. |
| 4 | 11259373 | Results are as follows: 1) LP T cells express an enzymatically active form of CD38, characterized by a modified ratio between cyclase and hydrolase functions; 2) LP T cells do not mobilize Ca2+ upon CD38 ligation, as seen in PB T cells (this condition is due to a lack in activation of PLC- g, constantly observed in PB T lymphocytes); 3) The early steps of CD38 signaling involve activation of lck, syk, and LAT; 4) Late events include synthesis and release of IL-2, IL-4, IL-5, IL-10, IFN-g and GM-CSF; 5) The uniqueness of the CD38 pathway in LP T cells is not caused by impaired interactions with the CD31 ligand. |
| 5 | 23939944 | Here we show that human umbilical cord blood (UCB)-derived CD34+CD38-/low hematopoietic stem cells can be successfully differentiated into functional, antigen-specific cytotoxic CD8+ T cells without direct stromal coculture or retroviral TCR transfection. |
| 6 | 23939944 | Surface-immobilized Notch ligands (DLL1) and stromal cell conditioned medium successfully induced the development of CD1a+CD7+ and CD4+CD8+ early T cells. |
| 7 | 23939944 | These cells, upon continued culture with cytomegalovirus (CMV) or influenza-A virus M1 (GIL) epitope-loaded human leukocyte antigen (HLA)-A*0201 tetramers, resulted in the generation of a polyclonal population of CMV-specific or GIL-specific CD8+ T cells, respectively. |
| 8 | 23939944 | Upon further activation with antigen-loaded target cells, these antigen-specific, stem cell-derived T cells exhibited cytolytic functionality, specifically CD107a surface mobilization, interferon gamma (IFNg) production, and Granzyme B secretion. |