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Gene Information
Gene symbol: HLA-DRB1
Gene name: major histocompatibility complex, class II, DR beta 1
HGNC ID: 4948
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCR5 | 1 hits |
| 2 | CTLA4 | 1 hits |
| 3 | HLA-B | 1 hits |
| 4 | HLA-DOB | 1 hits |
| 5 | IFNAR1 | 1 hits |
| 6 | IFNB1 | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | IL4 | 1 hits |
| 9 | IL7R | 1 hits |
| 10 | SKIV2L | 1 hits |
| 11 | TGFA | 1 hits |
| 12 | TGFB1 | 1 hits |
| 13 | TNF | 1 hits |
| 14 | TNXB | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15570643 | Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis. |
| 2 | 21067287 | Multiple sclerosis risk markers in HLA-DRA, HLA-C, and IFNG genes are associated with sex-specific childhood leukemia risk. |
| 3 | 21067287 | Two other SNPs in superkiller viralicidic activity 2-like and tenascin XB that are markers for systemic lupus erythematosus susceptibility showed female-specific associations but due to linkage disequilibrium with HLA-DRB1*15. |
| 4 | 22295566 | Complex association analysis of copaxone (glatiramer acetate) immunotherapy efficacy with allelic polymorphism in the number of immune response genes, which encode interferone beta (IFNB1), transforming growth factor beta1 (TGFB1), interferone gamma (IFNG), tumor necrosis factor (TNF), interferon alpha/beta receptor 1 (IFNAR1), CC chemokine receptor 5 (CCR5), interleukin 7 receptor alpha subunit (IL7RA), cytotoxic T-lymphocyte antigen 4 (CTLA4) and HLA class II histocompatibility antigen beta chain (DRB1) was performed with APSampler algorithm for 285 multiple sclerosis patients of Russian ethnicity. |
| 5 | 22295566 | The results show evidence for the contribution of polymorphic variants in CCRS, DRB1, IFNG, TGFB1, IFNAR1, IL7RA and, probably, TNF and CTLA4 genes to copaxone treatment response. |
| 6 | 22295566 | Single alleles of CCR5 and DRB1 genes are reliably associated with treatment efficacy. |
| 7 | 22295566 | Complex association analysis of copaxone (glatiramer acetate) immunotherapy efficacy with allelic polymorphism in the number of immune response genes, which encode interferone beta (IFNB1), transforming growth factor beta1 (TGFB1), interferone gamma (IFNG), tumor necrosis factor (TNF), interferon alpha/beta receptor 1 (IFNAR1), CC chemokine receptor 5 (CCR5), interleukin 7 receptor alpha subunit (IL7RA), cytotoxic T-lymphocyte antigen 4 (CTLA4) and HLA class II histocompatibility antigen beta chain (DRB1) was performed with APSampler algorithm for 285 multiple sclerosis patients of Russian ethnicity. |
| 8 | 22295566 | The results show evidence for the contribution of polymorphic variants in CCRS, DRB1, IFNG, TGFB1, IFNAR1, IL7RA and, probably, TNF and CTLA4 genes to copaxone treatment response. |
| 9 | 22295566 | Single alleles of CCR5 and DRB1 genes are reliably associated with treatment efficacy. |
| 10 | 22295566 | Complex association analysis of copaxone (glatiramer acetate) immunotherapy efficacy with allelic polymorphism in the number of immune response genes, which encode interferone beta (IFNB1), transforming growth factor beta1 (TGFB1), interferone gamma (IFNG), tumor necrosis factor (TNF), interferon alpha/beta receptor 1 (IFNAR1), CC chemokine receptor 5 (CCR5), interleukin 7 receptor alpha subunit (IL7RA), cytotoxic T-lymphocyte antigen 4 (CTLA4) and HLA class II histocompatibility antigen beta chain (DRB1) was performed with APSampler algorithm for 285 multiple sclerosis patients of Russian ethnicity. |
| 11 | 22295566 | The results show evidence for the contribution of polymorphic variants in CCRS, DRB1, IFNG, TGFB1, IFNAR1, IL7RA and, probably, TNF and CTLA4 genes to copaxone treatment response. |
| 12 | 22295566 | Single alleles of CCR5 and DRB1 genes are reliably associated with treatment efficacy. |