| # |
PMID |
Sentence |
| 1 |
12107440
|
Mutant MECP2 was expressed at normal transcript and protein levels, and exhibited no significant effect on acetylated histones or methyl-binding protein 3 (MBD3) levels.
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| 2 |
12107440
|
The allelic expression of three different imprinted genes (SNRPN, IPW and IGF2) was examined by RT-PCR and RFLP analysis, and demonstrated normal monoallelic expression of all RTT clones.
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| 3 |
12107440
|
We also examined the expression of five imprinted genes (SNRPN, IPW, NECDIN, H19 and IGF2) in RTT brain samples and observed exclusive monoallelic expression.
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| 4 |
12107440
|
In conclusion, our results do not support an essential role for either MeCP2 or HDAC in the silencing of several imprinted genes.
|
| 5 |
12107440
|
Mutant MECP2 was expressed at normal transcript and protein levels, and exhibited no significant effect on acetylated histones or methyl-binding protein 3 (MBD3) levels.
|
| 6 |
12107440
|
The allelic expression of three different imprinted genes (SNRPN, IPW and IGF2) was examined by RT-PCR and RFLP analysis, and demonstrated normal monoallelic expression of all RTT clones.
|
| 7 |
12107440
|
We also examined the expression of five imprinted genes (SNRPN, IPW, NECDIN, H19 and IGF2) in RTT brain samples and observed exclusive monoallelic expression.
|
| 8 |
12107440
|
In conclusion, our results do not support an essential role for either MeCP2 or HDAC in the silencing of several imprinted genes.
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| 9 |
12931271
|
IGFs, basic FGF, and glucose modulate proliferation and apoptosis induced by IFNgamma but not by IL-1beta in rat INS-1E beta-cells.
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| 10 |
12931271
|
We investigated the effects of glucose and beta-cell growth factors (IGF-I, IGF-II, bFGF) on growth and apoptosis in the presence and absence of apoptosis inducing cytokines (IFNgamma, Il-1beta, TNFalpha).
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| 11 |
12931271
|
The cytokines IFNg and IL-1beta, but not TNFalpha strongly induced INS-1E beta-cell apoptosis.
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| 12 |
12931271
|
Most importantly, IGF-II and bFGF inhibited apoptosis induced by IFNg, but not by IL-1beta.
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| 13 |
12931271
|
Cytokines IFNg and IL-1beta differentially interfere with intracellular signaling cascades stimulated by IGFs and bFGF or glucose, respectively.
|
| 14 |
12931271
|
IGFs, basic FGF, and glucose modulate proliferation and apoptosis induced by IFNgamma but not by IL-1beta in rat INS-1E beta-cells.
|
| 15 |
12931271
|
We investigated the effects of glucose and beta-cell growth factors (IGF-I, IGF-II, bFGF) on growth and apoptosis in the presence and absence of apoptosis inducing cytokines (IFNgamma, Il-1beta, TNFalpha).
|
| 16 |
12931271
|
The cytokines IFNg and IL-1beta, but not TNFalpha strongly induced INS-1E beta-cell apoptosis.
|
| 17 |
12931271
|
Most importantly, IGF-II and bFGF inhibited apoptosis induced by IFNg, but not by IL-1beta.
|
| 18 |
12931271
|
Cytokines IFNg and IL-1beta differentially interfere with intracellular signaling cascades stimulated by IGFs and bFGF or glucose, respectively.
|