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Gene Information

Gene symbol: IL17C

Gene name: interleukin 17C

HGNC ID: 5983

Synonyms: IL-17C, CX2, IL-21, MGC126884, MGC138401

Related Genes

# Gene Symbol Number of hits
1 CXCR5 1 hits
2 IFNG 1 hits
3 IL10 1 hits
4 IL12A 1 hits
5 IL2 1 hits
6 IL21 1 hits
7 IL4 1 hits
8 TGFA 1 hits

Related Sentences

# PMID Sentence
1 22466669 The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
2 22466669 Germinal centers require CD4⁺ follicular helper T cells (TFH cells), whose hallmark is expression of the transcriptional repressor Bcl-6, the chemokine receptor CXCR5 and interleukin 21 (IL-21).
3 22466669 To track the development and fate of TFH cells, we generated an IL-21 reporter mouse by introducing sequence encoding green fluorescent protein (GFP) into the Il21 locus; these mice had expression of IL-21–GFP in CD4⁺CXCR5⁺PD-1⁺ TFH cells.
4 22466669 IL-21–GFP⁺ TFH cells were multifunctional helper cells that coexpressed several cytokines, including interferon-g (IFN-g), IL-2 and IL-4.
5 22466669 The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
6 22466669 Germinal centers require CD4⁺ follicular helper T cells (TFH cells), whose hallmark is expression of the transcriptional repressor Bcl-6, the chemokine receptor CXCR5 and interleukin 21 (IL-21).
7 22466669 To track the development and fate of TFH cells, we generated an IL-21 reporter mouse by introducing sequence encoding green fluorescent protein (GFP) into the Il21 locus; these mice had expression of IL-21–GFP in CD4⁺CXCR5⁺PD-1⁺ TFH cells.
8 22466669 IL-21–GFP⁺ TFH cells were multifunctional helper cells that coexpressed several cytokines, including interferon-g (IFN-g), IL-2 and IL-4.
9 22466669 The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
10 22466669 Germinal centers require CD4⁺ follicular helper T cells (TFH cells), whose hallmark is expression of the transcriptional repressor Bcl-6, the chemokine receptor CXCR5 and interleukin 21 (IL-21).
11 22466669 To track the development and fate of TFH cells, we generated an IL-21 reporter mouse by introducing sequence encoding green fluorescent protein (GFP) into the Il21 locus; these mice had expression of IL-21–GFP in CD4⁺CXCR5⁺PD-1⁺ TFH cells.
12 22466669 IL-21–GFP⁺ TFH cells were multifunctional helper cells that coexpressed several cytokines, including interferon-g (IFN-g), IL-2 and IL-4.
13 22466669 The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
14 22466669 Germinal centers require CD4⁺ follicular helper T cells (TFH cells), whose hallmark is expression of the transcriptional repressor Bcl-6, the chemokine receptor CXCR5 and interleukin 21 (IL-21).
15 22466669 To track the development and fate of TFH cells, we generated an IL-21 reporter mouse by introducing sequence encoding green fluorescent protein (GFP) into the Il21 locus; these mice had expression of IL-21–GFP in CD4⁺CXCR5⁺PD-1⁺ TFH cells.
16 22466669 IL-21–GFP⁺ TFH cells were multifunctional helper cells that coexpressed several cytokines, including interferon-g (IFN-g), IL-2 and IL-4.
17 24256319 We show that the production of IL-10 by lipopolysaccharide-stimulated B cells is significantly enhanced by IL-12 and interferon-γ and negatively regulated by IL-21 and transforming growth factor-β.