Ignet

Gene Information

Gene symbol: IL7R

Gene name: interleukin 7 receptor

HGNC ID: 6024

Synonyms: CD127

Related Genes

#	Gene Symbol	Number of hits
1	AKT3	1 hits
2	CBLB	1 hits
3	CCR4	1 hits
4	CCR5	1 hits
5	CCR6	1 hits
6	CD27	1 hits
7	CD4	1 hits
8	CD8A	1 hits
9	CELIAC3	1 hits
10	CTLA4	1 hits
11	CX3CR1	1 hits
12	CXCR3	1 hits
13	DLG1	1 hits
14	EOMES	1 hits
15	FKBP1A	1 hits
16	FOXP3	1 hits
17	GZMB	1 hits
18	HLA-B	1 hits
19	HLA-DOB	1 hits
20	HLA-DRB1	1 hits
21	IFNAR1	1 hits
22	IFNB1	1 hits
23	IFNG	1 hits
24	IL10	1 hits
25	IL2	1 hits
26	IL2RA	1 hits
27	ISG20	1 hits
28	ITK	1 hits
29	JUN	1 hits
30	KLRD1	1 hits
31	MALT1	1 hits
32	MKI67	1 hits
33	NFATC2	1 hits
34	NOG	1 hits
35	PLCG1	1 hits
36	PRF1	1 hits
37	RBM12B	1 hits
38	SPRED1	1 hits
39	TGFA	1 hits
40	TGFB1	1 hits
41	TNF	1 hits
42	TNFRSF1B	1 hits
43	ZNF395	1 hits

Related Sentences

#	PMID	Sentence
1	20018909	Blood and decidual CD4(+) T cells from 18 healthy first-trimester pregnant women were analyzed for expression of Treg-cell markers (CD25, FOXP3, CD127, CTLA4, and human leukocyte antigen-DR [HLA-DR]), chemokine receptors (CCR4, CCR6, and CXCR3), and the proliferation antigen MKI67 by six-color flow cytometry.
2	20018909	Using chemokine receptor expression profiles of CCR4, CCR6, and CXCR3 as markers for T(H)1, T(H)2, and T(H)17 cells, we showed that T(H)17 cells were nearly absent in decidua, whereas T(H)2-cell frequencies were similar in blood and decidua.
3	20018909	CCR6(+) T(H)1 cells, reported to secrete high levels of interferon gamma (IFNG), were fewer, whereas the moderately IFNG-secreting CCR6(-) T(H)1 cells were more frequent in decidua compared with blood.
4	22295566	Complex association analysis of copaxone (glatiramer acetate) immunotherapy efficacy with allelic polymorphism in the number of immune response genes, which encode interferone beta (IFNB1), transforming growth factor beta1 (TGFB1), interferone gamma (IFNG), tumor necrosis factor (TNF), interferon alpha/beta receptor 1 (IFNAR1), CC chemokine receptor 5 (CCR5), interleukin 7 receptor alpha subunit (IL7RA), cytotoxic T-lymphocyte antigen 4 (CTLA4) and HLA class II histocompatibility antigen beta chain (DRB1) was performed with APSampler algorithm for 285 multiple sclerosis patients of Russian ethnicity.
5	22295566	The results show evidence for the contribution of polymorphic variants in CCRS, DRB1, IFNG, TGFB1, IFNAR1, IL7RA and, probably, TNF and CTLA4 genes to copaxone treatment response.
6	22295566	Single alleles of CCR5 and DRB1 genes are reliably associated with treatment efficacy.
7	22295566	Complex association analysis of copaxone (glatiramer acetate) immunotherapy efficacy with allelic polymorphism in the number of immune response genes, which encode interferone beta (IFNB1), transforming growth factor beta1 (TGFB1), interferone gamma (IFNG), tumor necrosis factor (TNF), interferon alpha/beta receptor 1 (IFNAR1), CC chemokine receptor 5 (CCR5), interleukin 7 receptor alpha subunit (IL7RA), cytotoxic T-lymphocyte antigen 4 (CTLA4) and HLA class II histocompatibility antigen beta chain (DRB1) was performed with APSampler algorithm for 285 multiple sclerosis patients of Russian ethnicity.
8	22295566	The results show evidence for the contribution of polymorphic variants in CCRS, DRB1, IFNG, TGFB1, IFNAR1, IL7RA and, probably, TNF and CTLA4 genes to copaxone treatment response.
9	22295566	Single alleles of CCR5 and DRB1 genes are reliably associated with treatment efficacy.
10	22735807	We have previously shown that vaccination with the natural tumor peptide Melan-A-induced T cells with superior effector functions as compared with vaccination with the analog peptide optimized for enhanced HLA-A*0201 binding.
11	22735807	Here we found that natural peptide vaccination induced tumor-reactive CD8 T cells with frequent coexpression of both memory/homing-associated genes (CD27, IL7R, EOMES, CXCR3, and CCR5) and effector-related genes (IFNG, KLRD1, PRF1, and GZMB), comparable with protective Epstein-Barr virus-specific and cytomegalovirus-specific T cells.
12	22984568	Additional validation strategies included significant association of single nucleotide polymorphisms (SNPs) in signature genes with sarcoidosis susceptibility and severity (unbiased signature genes - CX3CR1, FKBP1A, NOG, RBM12B, SENS3, TSHZ2; T cell/JAK-STAT pathway genes such as AKT3, CBLB, DLG1, IFNG, IL2RA, IL7R, ITK, JUN, MALT1, NFATC2, PLCG1, SPRED1).
13	23964278	The in vitro induced CD25(hi)TNFR2(+) T cells express a conventional regulatory T cells phenotype FOXP3(+)CTLA4(+)CD127(lo/-), but produce effector and immunoregulatory cytokines including IL-2, IL-10, and IFN-g.