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Gene Information

Gene symbol: TNFRSF8

Gene name: tumor necrosis factor receptor superfamily, member 8

HGNC ID: 11923

Synonyms: KI-1

Related Genes

# Gene Symbol Number of hits
1 IL10 1 hits
2 IL12A 1 hits
3 IL2 1 hits

Related Sentences

# PMID Sentence
1 15688386 Simultaneous targeting of IL2 and IL12 to Hodgkin's lymphoma cells enhances activation of resting NK cells and tumor cell lysis.
2 15688386 To revert cellular anergy against H/RS cells, we generated an anti-CD30-antibody-interleukin-(IL)-2 and an anti-CD30-antibody-IL12 fusion protein that target IL2 and IL12, respectively, specifically to CD30+ H/RS cells.
3 22912446 Downregulated genes in tumorous spleens mainly enriched in the cytokine-cytokine receptor interaction pathway, and commonly investigated genes in Marek's disease study, IL6, IL18, IFNA, and IFNG were nondifferentially expressed, which indicates host inflammatory response was impaired.
4 22912446 The IL10 and TNFRSF8 genes were upregulated in tumorous spleens.